Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita
Root-knot nematodes of the genus Meloidogyne are biotrophic plant parasites that exhibit different reproduction modes, ranging from classical amphimixis to obligatory mitotic parthenogenesis (apomixis), depending on the species. Meloidogyne incognita, an apomictic species, exhibits a worldwide distr...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-06-01
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| Series: | Frontiers in Physiology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00211/full |
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| author | Laetitia ePerfus-Barbeoch Laetitia ePerfus-Barbeoch Laetitia ePerfus-Barbeoch Philippe eCastagnone-Sereno Philippe eCastagnone-Sereno Philippe eCastagnone-Sereno Michael eReichelt Sara eFneich Sara eFneich David eRoquis David eRoquis Loris ePratx Loris ePratx Loris ePratx Celine eCosseau Celine eCosseau Christoph eGrunau Christoph eGrunau Pierre eAbad Pierre eAbad Pierre eAbad |
| author_facet | Laetitia ePerfus-Barbeoch Laetitia ePerfus-Barbeoch Laetitia ePerfus-Barbeoch Philippe eCastagnone-Sereno Philippe eCastagnone-Sereno Philippe eCastagnone-Sereno Michael eReichelt Sara eFneich Sara eFneich David eRoquis David eRoquis Loris ePratx Loris ePratx Loris ePratx Celine eCosseau Celine eCosseau Christoph eGrunau Christoph eGrunau Pierre eAbad Pierre eAbad Pierre eAbad |
| author_sort | Laetitia ePerfus-Barbeoch |
| collection | DOAJ |
| description | Root-knot nematodes of the genus Meloidogyne are biotrophic plant parasites that exhibit different reproduction modes, ranging from classical amphimixis to obligatory mitotic parthenogenesis (apomixis), depending on the species. Meloidogyne incognita, an apomictic species, exhibits a worldwide distribution and a wide host range affecting more than 3,000 plant species. Furthermore, evidences suggest that apomixis does not prevent M. incognita from adapting to its environment in contrast to what is expected from mitotic parthenogenesis that should theoretically produce clonal progenies. This raises questions about mechanisms of genome plasticity leading to genetic variation and adaptive evolution in apomictic animals. We reasoned that epigenetic mechanisms might in part be responsible for the generation of phenotypic variants that provide potential for rapid adaptation. We investigated therefore the principal carriers of epigenetic information, DNA methylation and post-translational histone modifications. Even if M. incognita possesses the epigenetic machinery i.e. chromatin modifying enzymes, 5-methyl-cytosine and 5-hydroxy-methyl-cytosine content is absent or very weak. In contrast, we demonstrated that the canonical histone modifications are present and chromatin shows typical nucleosome structure. This work is the first characterization of carriers of epigenetic information in M. incognita and constitutes a preamble to further investigate whether M. incognita development and its adaptation to plant hosts are under epigenetic control. |
| first_indexed | 2024-12-10T13:57:44Z |
| format | Article |
| id | doaj.art-f95101adfdf54c71b5d30ccf4d1807e2 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-10T13:57:44Z |
| publishDate | 2014-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-f95101adfdf54c71b5d30ccf4d1807e22022-12-22T01:45:54ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2014-06-01510.3389/fphys.2014.0021178141Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognitaLaetitia ePerfus-Barbeoch0Laetitia ePerfus-Barbeoch1Laetitia ePerfus-Barbeoch2Philippe eCastagnone-Sereno3Philippe eCastagnone-Sereno4Philippe eCastagnone-Sereno5Michael eReichelt6Sara eFneich7Sara eFneich8David eRoquis9David eRoquis10Loris ePratx11Loris ePratx12Loris ePratx13Celine eCosseau14Celine eCosseau15Christoph eGrunau16Christoph eGrunau17Pierre eAbad18Pierre eAbad19Pierre eAbad20Université de Nice Sophia-AntipolisINRACNRSUniversité de Nice Sophia-AntipolisINRACNRSMPIUniversité de Perpignan Via DomitiaCNRSUniversité de Perpignan Via DomitiaCNRSUniversité de Nice Sophia-AntipolisINRACNRSUniversité de Perpignan Via DomitiaCNRSUniversité de Perpignan Via DomitiaCNRSUniversité de Nice Sophia-AntipolisINRACNRSRoot-knot nematodes of the genus Meloidogyne are biotrophic plant parasites that exhibit different reproduction modes, ranging from classical amphimixis to obligatory mitotic parthenogenesis (apomixis), depending on the species. Meloidogyne incognita, an apomictic species, exhibits a worldwide distribution and a wide host range affecting more than 3,000 plant species. Furthermore, evidences suggest that apomixis does not prevent M. incognita from adapting to its environment in contrast to what is expected from mitotic parthenogenesis that should theoretically produce clonal progenies. This raises questions about mechanisms of genome plasticity leading to genetic variation and adaptive evolution in apomictic animals. We reasoned that epigenetic mechanisms might in part be responsible for the generation of phenotypic variants that provide potential for rapid adaptation. We investigated therefore the principal carriers of epigenetic information, DNA methylation and post-translational histone modifications. Even if M. incognita possesses the epigenetic machinery i.e. chromatin modifying enzymes, 5-methyl-cytosine and 5-hydroxy-methyl-cytosine content is absent or very weak. In contrast, we demonstrated that the canonical histone modifications are present and chromatin shows typical nucleosome structure. This work is the first characterization of carriers of epigenetic information in M. incognita and constitutes a preamble to further investigate whether M. incognita development and its adaptation to plant hosts are under epigenetic control.http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00211/fullApomixisDNA MethylationClonesNucleosomeMeloidogyne incognitaPlant-parasitic nematodes |
| spellingShingle | Laetitia ePerfus-Barbeoch Laetitia ePerfus-Barbeoch Laetitia ePerfus-Barbeoch Philippe eCastagnone-Sereno Philippe eCastagnone-Sereno Philippe eCastagnone-Sereno Michael eReichelt Sara eFneich Sara eFneich David eRoquis David eRoquis Loris ePratx Loris ePratx Loris ePratx Celine eCosseau Celine eCosseau Christoph eGrunau Christoph eGrunau Pierre eAbad Pierre eAbad Pierre eAbad Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita Frontiers in Physiology Apomixis DNA Methylation Clones Nucleosome Meloidogyne incognita Plant-parasitic nematodes |
| title | Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita |
| title_full | Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita |
| title_fullStr | Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita |
| title_full_unstemmed | Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita |
| title_short | Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita |
| title_sort | elucidating the molecular bases of epigenetic inheritance in non model invertebrates the case of the root knot nematode meloidogyne incognita |
| topic | Apomixis DNA Methylation Clones Nucleosome Meloidogyne incognita Plant-parasitic nematodes |
| url | http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00211/full |
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