Improved Neomycin Sulfate Potency in <i>Streptomyces fradiae</i> Using Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis and Fermentation Medium Optimization

Improved Neomycin Sulfate Potency in <i>Streptomyces fradiae</i> Using Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis and Fermentation Medium Optimization

To improve the screening efficiency of high-yield neomycin sulfate (NM) <i>Streptomyces fradiae</i> strains after mutagenesis, a high-throughput screening method using streptomycin resistance prescreening (8 μg/mL) and a 24-deep well plates/microplate reader (trypan blue spectrophotometr...

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Bibliographic Details
Main Authors: Fei Yu, Min Zhang, Junfeng Sun, Fang Wang, Xiangfei Li, Yan Liu, Zhou Wang, Xinrui Zhao, Jianghua Li, Jian Chen, Guocheng Du, Zhenglian Xue
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Microorganisms
Subjects:
neomycin sulfate (NM)
<i>Streptomyces fradiae</i>
high-throughput screening
atmospheric and room temperature plasma (ARTP) mutagenesis
fermentation medium optimization
Online Access:https://www.mdpi.com/2076-2607/10/1/94

Internet

https://www.mdpi.com/2076-2607/10/1/94

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