Cauli: a mouse strain with an Ift140 mutation that results in a skeletal ciliopathy modelling Jeune syndrome.

Cauli: a mouse strain with an Ift140 mutation that results in a skeletal ciliopathy modelling Jeune syndrome.

Cilia are architecturally complex organelles that protrude from the cell membrane and have signalling, sensory and motility functions that are central to normal tissue development and homeostasis. There are two broad categories of cilia; motile and non-motile, or primary, cilia. The central role of...

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Main Authors: Kerry A Miller, Casey J Ah-Cann, Megan F Welfare, Tiong Y Tan, Kate Pope, Georgina Caruana, Mary-Louise Freckmann, Ravi Savarirayan, John F Bertram, Michael S Dobbie, John F Bateman, Peter G Farlie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3757063?pdf=render

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