Artificial-Intelligence-Based Imaging Analysis of Stem Cells: A Systematic Scoping Review

This systematic scoping review aims to map and identify the available artificial-intelligence-based techniques for imaging analysis, the characterization of stem cell differentiation, and trans-differentiation pathways. On the ninth of March 2022, data were collected from five electronic databases (...

Full description

Bibliographic Details
Main Authors: Julien Issa, Mazen Abou Chaar, Bartosz Kempisty, Lukasz Gasiorowski, Raphael Olszewski, Paul Mozdziak, Marta Dyszkiewicz-Konwińska
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/10/1412
Description
Summary:This systematic scoping review aims to map and identify the available artificial-intelligence-based techniques for imaging analysis, the characterization of stem cell differentiation, and trans-differentiation pathways. On the ninth of March 2022, data were collected from five electronic databases (PubMed, Medline, Web of Science, Cochrane, and Scopus) and manual citation searching; all data were gathered in Zotero 5.0. A total of 4422 articles were collected after deduplication; only twenty-seven studies were included in this systematic scoping review after a two-phase screening against inclusion criteria by two independent reviewers. The amount of research in this field is significantly increasing over the years. While the current state of artificial intelligence (AI) can tackle a multitude of medical problems, the consensus amongst researchers remains that AI still falls short in multiple ways that investigators should examine, ranging from the quality of images used in training sets and appropriate sample size, as well as the unexpected events that may occur which the algorithm cannot predict.
ISSN:2079-7737