Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking.

Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking.

Zwitterionic capsular polysaccharides (ZPS) of commensal bacteria are characterized by having both positive and negative charged substituents on each repeating unit of a highly repetitive structure that has an alpha-helix configuration. In this paper we look at the immune response of CD8(+) T cells...

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Bibliographic Details
Main Authors: Janina Mertens, Mario Fabri, Alessandra Zingarelli, Torsten Kubacki, Sonja Meemboor, Laura Groneck, Jens Seeger, Martina Bessler, Helena Hafke, Margarete Odenthal, Joan G Bieler, Christoph Kalka, Jonathan P Schneck, Hamid Kashkar, Wiltrud M Kalka-Moll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2742891?pdf=render

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