ONCE MORE ABOUT PHAGE THERAPY: WHAT IS RIGHT, AND WHAT IS NOT

A little more than 100 years ago the article “An investigation on the nature of ultra-microscopic viruses” by the English physician and researcher F. Twort was published in The Lancet. Twort described the phenomenon of transparent spots which occurred on the bacterial lawn when he worked with bacter...

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Main Authors: V. M. Popova, E. L. Zhilenkov, A. Y. Zurabov
Format: Article
Language:Russian
Published: Remedium Group LLC 2016-12-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/1507
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author V. M. Popova
E. L. Zhilenkov
A. Y. Zurabov
author_facet V. M. Popova
E. L. Zhilenkov
A. Y. Zurabov
author_sort V. M. Popova
collection DOAJ
description A little more than 100 years ago the article “An investigation on the nature of ultra-microscopic viruses” by the English physician and researcher F. Twort was published in The Lancet. Twort described the phenomenon of transparent spots which occurred on the bacterial lawn when he worked with bacterial cultures using a petri dish. He examined the spots and found zones of dead bacteria. The spots were transmissible: they appeared on other dishes once transferred to a new lawn. Twort, failing to give a convincing explanation for this phenomenon, proposed three hypotheses:  it could be an unusual manifestation of the bacterial life cycle, or an enzyme produced by the bacteria themselves or some sort of “ultra-microscopic virus” which could cause the death of bacteria. Having voiced his hypotheses, Tvort let the matter drop, but many believe that with the article began the era of bacteriophages.
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spelling doaj.art-f95fdb0e01f44192a0457c57288e1b092023-04-23T06:56:55ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902016-12-01016445010.21518/2079-701X-2016-16-44-501503ONCE MORE ABOUT PHAGE THERAPY: WHAT IS RIGHT, AND WHAT IS NOTV. M. Popova0E. L. Zhilenkov1A. Y. Zurabov2Micromir SPC, MoscowMicromir SPC, MoscowMicromir SPC, MoscowA little more than 100 years ago the article “An investigation on the nature of ultra-microscopic viruses” by the English physician and researcher F. Twort was published in The Lancet. Twort described the phenomenon of transparent spots which occurred on the bacterial lawn when he worked with bacterial cultures using a petri dish. He examined the spots and found zones of dead bacteria. The spots were transmissible: they appeared on other dishes once transferred to a new lawn. Twort, failing to give a convincing explanation for this phenomenon, proposed three hypotheses:  it could be an unusual manifestation of the bacterial life cycle, or an enzyme produced by the bacteria themselves or some sort of “ultra-microscopic virus” which could cause the death of bacteria. Having voiced his hypotheses, Tvort let the matter drop, but many believe that with the article began the era of bacteriophages.https://www.med-sovet.pro/jour/article/view/1507bacteriophagephage therapyantibioticsmicrobiome
spellingShingle V. M. Popova
E. L. Zhilenkov
A. Y. Zurabov
ONCE MORE ABOUT PHAGE THERAPY: WHAT IS RIGHT, AND WHAT IS NOT
Медицинский совет
bacteriophage
phage therapy
antibiotics
microbiome
title ONCE MORE ABOUT PHAGE THERAPY: WHAT IS RIGHT, AND WHAT IS NOT
title_full ONCE MORE ABOUT PHAGE THERAPY: WHAT IS RIGHT, AND WHAT IS NOT
title_fullStr ONCE MORE ABOUT PHAGE THERAPY: WHAT IS RIGHT, AND WHAT IS NOT
title_full_unstemmed ONCE MORE ABOUT PHAGE THERAPY: WHAT IS RIGHT, AND WHAT IS NOT
title_short ONCE MORE ABOUT PHAGE THERAPY: WHAT IS RIGHT, AND WHAT IS NOT
title_sort once more about phage therapy what is right and what is not
topic bacteriophage
phage therapy
antibiotics
microbiome
url https://www.med-sovet.pro/jour/article/view/1507
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