Betulin-3,28-diphosphate as a Component of Combination Cytostatic Drugs for the Treatment of Ehrlich Ascites Carcinoma In Vitro and In Vivo Experiments

Betulin-3,28-diphosphate as a Component of Combination Cytostatic Drugs for the Treatment of Ehrlich Ascites Carcinoma In Vitro and In Vivo Experiments

The activity of betulin-3,28-diphosphate (BDP) in combination with the cytostatics such as 5-fluorouracil (5-FU) and hydrazine sulfate (HS) was demonstrated by using the transplanted Ehrlich ascites carcinoma (EAC) in mice. The dose-dependent effect of combination drugs BDP + HS and BDP + 5-FU was r...

Full description

Bibliographic Details
Main Authors: Olga Vorobyova, Olga Deryabina, Darina Malygina, Nadezhda Plotnikova, Anna Solovyeva, Kseniya Belyaeva, Nina Melnikova
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Scientia Pharmaceutica
Subjects:
Ehrlich carcinoma
betulin-3,28-diphosphate
5-fluorouracil
hydrazine sulfate
antioxidant activity
Online Access:http://www.mdpi.com/2218-0532/86/2/17

Internet

http://www.mdpi.com/2218-0532/86/2/17

Similar Items