Understanding the Emerging Link Between Circadian Rhythm, Nrf2 Pathway, and Breast Cancer to Overcome Drug Resistance

Understanding the Emerging Link Between Circadian Rhythm, Nrf2 Pathway, and Breast Cancer to Overcome Drug Resistance

The levels of different molecules in the cell are rhythmically cycled by the molecular clock present at the cellular level. The circadian rhythm is closely linked to the metabolic processes in the cells by an underlying mechanism whose intricacies need to be thoroughly investigated. Nevertheless, Nr...

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Bibliographic Details
Main Authors: Supriya Bevinakoppamath, Shobha Chikkavaddaragudi Ramachandra, Anshu Kumar Yadav, Vijaya Basavaraj, Prashant Vishwanath, Akila Prashant
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
NRF2–KEAP1 pathway
breast cancer
BMAL-1
circadian rhythm
chemoresistance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.719631/full

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