On the prebiotic selection of nucleotide anomers: A computational study
Present-day known predominance of the β- over the α-anomers in nucleosides and nucleotides emerges from a thermodynamic analysis of their assembly from their components, i.e. bases, sugars, and a phosphate group. Furthermore, the incorporation of uracil into RNA and thymine into DNA rather than the...
Main Authors: | Lázaro A.M. Castanedo, Chérif F. Matta |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-06-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022009458 |
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