Miconazole alleviates peripheral nerve crush injury by mediating a macrophage phenotype change through the NF‐κB pathway

Miconazole alleviates peripheral nerve crush injury by mediating a macrophage phenotype change through the NF‐κB pathway

Abstract Background Peripheral nerve injury (PNI) causes motor and sensory defects, has strong impact on life quality and still has no effective therapy. Miconazole is one of the most widely used antifungal drugs; the aims of the study were to investigate the effects of miconazole during sciatic ner...

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Bibliographic Details
Main Authors: Liangliang Zhang, Xiuju Chen, Zengyun Liu, Qingluan Han, Liguo Tang, Zhen Tian, Zhiyong Ren, Cunmin Rong, Hui Xu
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Brain and Behavior
Subjects:
macrophage
miconazole
NF‐κB
peripheral nerve injury
polarization
Online Access:https://doi.org/10.1002/brb3.1400

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