CD82 attenuates TGF-β1-mediated epithelial-mesenchymal transition by blocking smad-dependent signaling in ARPE-19 cells

CD82 attenuates TGF-β1-mediated epithelial-mesenchymal transition by blocking smad-dependent signaling in ARPE-19 cells

In retinal pigment epithelial (RPE) cells, transforming growth factor-beta (TGF-β) plays a critical role in epithelial-mesenchymal transition (EMT), which contributes to various fibrotic retinal disorders. In the present study, we investigated the effect of recombinant human cluster of differentiati...

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Bibliographic Details
Main Authors:	Hyesook Lee, Jung-Hwa Han, Yun Jeong Kang, Hyun Hwangbo, Aeseon Yoon, Hyung-Sik Kim, Dongjun Lee, Soo Yong Lee, Byung Hyun Choi, Jae-Joon Kim, Seo Rin Kim, Yung Hyun Choi, Jin Hur
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Pharmacology
Subjects:	epithelial-mesenchymal transition (EMT) fibrotic retinal disorders recombinant human cluster of differentiation 82 (rhCD82) retinal pigment epithelial (RPE) transforming growth factor-beta (TGF-β)
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.991056/full

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