Analysis of Characteristics, Pathogens and Drug Resistance of Urinary Tract Infection Associated with Long-Term Indwelling Double-J Stent
Yuehua Li,1 Li Jiang,2 Shengjun Luo,2 Daixing Hu,2 Xin Zhao,2 Guozhi Zhao,2 Wei Tang,2 Yu Guo3 1Department of Urology, University-Town Hospital of Chongqing Medical University, Chongqing, 400000, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Chongqing Medical U...
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| Format: | Article |
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Dove Medical Press
2023-04-01
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| Series: | Infection and Drug Resistance |
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| Online Access: | https://www.dovepress.com/analysis-of-characteristics-pathogens-and-drug-resistance-of-urinary-t-peer-reviewed-fulltext-article-IDR |
| _version_ | 1827968865738424320 |
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| author | Li Y Jiang L Luo S Hu D Zhao X Zhao G Tang W Guo Y |
| author_facet | Li Y Jiang L Luo S Hu D Zhao X Zhao G Tang W Guo Y |
| author_sort | Li Y |
| collection | DOAJ |
| description | Yuehua Li,1 Li Jiang,2 Shengjun Luo,2 Daixing Hu,2 Xin Zhao,2 Guozhi Zhao,2 Wei Tang,2 Yu Guo3 1Department of Urology, University-Town Hospital of Chongqing Medical University, Chongqing, 400000, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400000, People’s Republic of China; 3Department of Urology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400000, People’s Republic of ChinaCorrespondence: Yu Guo, Department of Urology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400000, People’s Republic of China, Tel/Fax +8623 67665886, Email medicale123@163.comObjective: To investigate the characteristics, pathogens and drug resistance of urinary tract infection (UTI) associated with long-term indwelling double-J stent.Methods: The clinical data of 102 patients with urinary tract infection associated with long-term indwelling double-J stent in University-Town Hospital of Chongqing Medical University and Chongqing Traditional Chinese Medicine Hospital from September 2010 to July 2022 were collected retrospectively, and the difference between etiological characteristics were analyzed. Urine and double-J stent samples of patients were collected for pathogen identification and drug sensitivity test.Results: A total of 102 patients, 39 (38.23%) males and 63 (61.77%) females, aged 24– 72 years, with a median age of 48 years, were included in this study. Urinary calculi (40.20%) and ureteral stricture (24.50%) were the main causes of urinary tract infection associated with long-term indwelling double-J stent. Among the patients with urinary tract infection caused by double-J stent, female patients were higher than male patients (61.77% vs 38.23%). In terms of positive rate of pathogenic bacteria culture, the rate of double-J stent was higher than that of urine (67.65% vs 35.29%). The main pathogenic bacteria in urine were Escherichia coli (30.55%) of Gram negative bacteria, while the main pathogenic bacteria in double-J stent were enterococcus faecalis (27.53%) of Gram positive bacteria. The resistance rate of Gram positive bacteria in double-J stent to vancomycin, ciprofloxacin, meropenem and piperacillin/tazobactam was significantly higher than that in urine (P< 0.05). The resistance rate of Gram negative bacteria in double-J stent to imipenem, cefepime, piperacillin/tazobactam, meropenem and cefoperazone/sulbactam was significantly higher than that in urine (P< 0.05).Conclusion: Double-J stent associated urinary tract infection is more common in women than in men. Escherichia coli and Enterococcus faecalis are the main pathogens, and the pathogens show strong drug resistance.Keywords: double-J stent, biofilm, pathogens, urinary tract infection, drug resistance, drug resistant bacteria, infection |
| first_indexed | 2024-04-09T18:29:17Z |
| format | Article |
| id | doaj.art-f9667a24cd4341b5a2c8b775fde78534 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-04-09T18:29:17Z |
| publishDate | 2023-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-f9667a24cd4341b5a2c8b775fde785342023-04-11T19:04:59ZengDove Medical PressInfection and Drug Resistance1178-69732023-04-01Volume 162089209682902Analysis of Characteristics, Pathogens and Drug Resistance of Urinary Tract Infection Associated with Long-Term Indwelling Double-J StentLi YJiang LLuo SHu DZhao XZhao GTang WGuo YYuehua Li,1 Li Jiang,2 Shengjun Luo,2 Daixing Hu,2 Xin Zhao,2 Guozhi Zhao,2 Wei Tang,2 Yu Guo3 1Department of Urology, University-Town Hospital of Chongqing Medical University, Chongqing, 400000, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400000, People’s Republic of China; 3Department of Urology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400000, People’s Republic of ChinaCorrespondence: Yu Guo, Department of Urology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400000, People’s Republic of China, Tel/Fax +8623 67665886, Email medicale123@163.comObjective: To investigate the characteristics, pathogens and drug resistance of urinary tract infection (UTI) associated with long-term indwelling double-J stent.Methods: The clinical data of 102 patients with urinary tract infection associated with long-term indwelling double-J stent in University-Town Hospital of Chongqing Medical University and Chongqing Traditional Chinese Medicine Hospital from September 2010 to July 2022 were collected retrospectively, and the difference between etiological characteristics were analyzed. Urine and double-J stent samples of patients were collected for pathogen identification and drug sensitivity test.Results: A total of 102 patients, 39 (38.23%) males and 63 (61.77%) females, aged 24– 72 years, with a median age of 48 years, were included in this study. Urinary calculi (40.20%) and ureteral stricture (24.50%) were the main causes of urinary tract infection associated with long-term indwelling double-J stent. Among the patients with urinary tract infection caused by double-J stent, female patients were higher than male patients (61.77% vs 38.23%). In terms of positive rate of pathogenic bacteria culture, the rate of double-J stent was higher than that of urine (67.65% vs 35.29%). The main pathogenic bacteria in urine were Escherichia coli (30.55%) of Gram negative bacteria, while the main pathogenic bacteria in double-J stent were enterococcus faecalis (27.53%) of Gram positive bacteria. The resistance rate of Gram positive bacteria in double-J stent to vancomycin, ciprofloxacin, meropenem and piperacillin/tazobactam was significantly higher than that in urine (P< 0.05). The resistance rate of Gram negative bacteria in double-J stent to imipenem, cefepime, piperacillin/tazobactam, meropenem and cefoperazone/sulbactam was significantly higher than that in urine (P< 0.05).Conclusion: Double-J stent associated urinary tract infection is more common in women than in men. Escherichia coli and Enterococcus faecalis are the main pathogens, and the pathogens show strong drug resistance.Keywords: double-J stent, biofilm, pathogens, urinary tract infection, drug resistance, drug resistant bacteria, infectionhttps://www.dovepress.com/analysis-of-characteristics-pathogens-and-drug-resistance-of-urinary-t-peer-reviewed-fulltext-article-IDRdouble-j stentbiofilmpathogensurinary tract infectiondrug resistancedrug resistant bacteriainfection. |
| spellingShingle | Li Y Jiang L Luo S Hu D Zhao X Zhao G Tang W Guo Y Analysis of Characteristics, Pathogens and Drug Resistance of Urinary Tract Infection Associated with Long-Term Indwelling Double-J Stent Infection and Drug Resistance double-j stent biofilm pathogens urinary tract infection drug resistance drug resistant bacteria infection. |
| title | Analysis of Characteristics, Pathogens and Drug Resistance of Urinary Tract Infection Associated with Long-Term Indwelling Double-J Stent |
| title_full | Analysis of Characteristics, Pathogens and Drug Resistance of Urinary Tract Infection Associated with Long-Term Indwelling Double-J Stent |
| title_fullStr | Analysis of Characteristics, Pathogens and Drug Resistance of Urinary Tract Infection Associated with Long-Term Indwelling Double-J Stent |
| title_full_unstemmed | Analysis of Characteristics, Pathogens and Drug Resistance of Urinary Tract Infection Associated with Long-Term Indwelling Double-J Stent |
| title_short | Analysis of Characteristics, Pathogens and Drug Resistance of Urinary Tract Infection Associated with Long-Term Indwelling Double-J Stent |
| title_sort | analysis of characteristics pathogens and drug resistance of urinary tract infection associated with long term indwelling double j stent |
| topic | double-j stent biofilm pathogens urinary tract infection drug resistance drug resistant bacteria infection. |
| url | https://www.dovepress.com/analysis-of-characteristics-pathogens-and-drug-resistance-of-urinary-t-peer-reviewed-fulltext-article-IDR |
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