LncRNA HOXA11-AS promotes glioma malignant phenotypes and reduces its sensitivity to ROS via Tpl2-MEK1/2-ERK1/2 pathway

LncRNA HOXA11-AS promotes glioma malignant phenotypes and reduces its sensitivity to ROS via Tpl2-MEK1/2-ERK1/2 pathway

Abstract Our previous studies showed that dysregulation of the long noncoding RNA (lncRNA) HOXA11-AS plays an important role in the development of glioma. However, the molecular mechanism of HOXA11-AS in glioma remains largely unknown. In this study, we explore the molecular mechanisms underlying ab...

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Bibliographic Details
Main Authors: Cheng Wei, Xiaoyang Zhang, Dazhao Peng, Xu Zhang, Haizhen Guo, Yalin Lu, Lin Luo, Bo Wang, Zesheng Li, Yingjie He, Xuezhi Du, Shu Zhang, Hao Liang, Shenghui Li, Sheng Wang, Lei Han, Jianning Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05393-5

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