Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in Taiwan
Under-utilization of Papanicolaou (Pap) smear causes a gap in the prevention of cervical neoplasms. A prospective population-based study was conducted investigating whether a self-sampling human papillomavirus (HPV) test was feasible for under-users of Pap smear and factors associated with under-scr...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-12-01
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| Series: | Journal of the Formosan Medical Association |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664615003538 |
| _version_ | 1818997681685528576 |
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| author | Hung-Hsueh Chou Huei-Jean Huang Hui-Hsin Cheng Chee-Jen Chang Lan-Yan Yang Chu-Chun Huang Wei-Yang Chang Swei Hsueh Angel Chao Chin-Jung Wang Yun-Hsin Tang Cheng-Tao Lin Jian-Tai Qiu Min-Yu Chen Chao-Yu Chen Kuan-Gen Huang Tzu-Chun Tsai Ting-Chang Chang Chyong-Huey Lai |
| author_facet | Hung-Hsueh Chou Huei-Jean Huang Hui-Hsin Cheng Chee-Jen Chang Lan-Yan Yang Chu-Chun Huang Wei-Yang Chang Swei Hsueh Angel Chao Chin-Jung Wang Yun-Hsin Tang Cheng-Tao Lin Jian-Tai Qiu Min-Yu Chen Chao-Yu Chen Kuan-Gen Huang Tzu-Chun Tsai Ting-Chang Chang Chyong-Huey Lai |
| author_sort | Hung-Hsueh Chou |
| collection | DOAJ |
| description | Under-utilization of Papanicolaou (Pap) smear causes a gap in the prevention of cervical neoplasms. A prospective population-based study was conducted investigating whether a self-sampling human papillomavirus (HPV) test was feasible for under-users of Pap smear and factors associated with under-screening in Taiwan.
Methods: Women not having Pap smear screening for > 5 years were invited to participate in this study. Invitation letters and educational brochures were mailed to 4% of randomly selected eligible women from Taoyuan City, Taiwan, and responders received an HPV self-sampling kit. Those with HPV-positive results were recalled for a Pap smear and colposcopy.
Results: Between March 2010 and June 2012, 10,693 women were invited, 354 responded (3.3%), and 282 (2.6%) gave valid informed consent, answered the questionnaire, and submitted HPV samples. The median age of enrolled women was 48.1 years. Forty-seven women (16.7%) had a positive HPV test, and 14 women accepted further survey to find two CIN2+. Another two cases of CIN2+ were identified from a national registry database. The cost of direct mailing self-samplers was less than that done on request (from NT$434,866 to NT$164,229, response rate of 5% to 15%, respectively, versus NT$683,957 for detecting 1 CIN2+). Reasons for not attending screening included lack of time, embarrassment, assumed low risk, fear of positive results, and perceived potential pain. Among the responders, 90.8% found the method acceptable.
Conclusion: Our study indicated that different approaches (e.g., direct mailing self-samplers to under-users and/or various educational interventions) must be explored to improve coverage in populations with culture characteristics similar to Taiwan. |
| first_indexed | 2024-12-20T21:49:30Z |
| format | Article |
| id | doaj.art-f96fdd7260944e709bcd8d6b9567e6b3 |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-20T21:49:30Z |
| publishDate | 2016-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-f96fdd7260944e709bcd8d6b9567e6b32022-12-21T19:25:36ZengElsevierJournal of the Formosan Medical Association0929-66462016-12-01115121089109610.1016/j.jfma.2015.10.014Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in TaiwanHung-Hsueh Chou0Huei-Jean Huang1Hui-Hsin Cheng2Chee-Jen Chang3Lan-Yan Yang4Chu-Chun Huang5Wei-Yang Chang6Swei Hsueh7Angel Chao8Chin-Jung Wang9Yun-Hsin Tang10Cheng-Tao Lin11Jian-Tai Qiu12Min-Yu Chen13Chao-Yu Chen14Kuan-Gen Huang15Tzu-Chun Tsai16Ting-Chang Chang17Chyong-Huey Lai18Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanGynecologic Cancer Research Center, Chang Gung Memorial Hospital, Taoyuan, TaiwanResearch Center of Clinical Informatics and Medical Statistics, Chang Gung University, Taoyuan, TaiwanGynecologic Cancer Research Center, Chang Gung Memorial Hospital, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanClinical Trial Center, Chang Gung Memorial Hospital, Taoyuan, TaiwanGynecologic Cancer Research Center, Chang Gung Memorial Hospital, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Public Health, Taoyuan City Government, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, TaiwanUnder-utilization of Papanicolaou (Pap) smear causes a gap in the prevention of cervical neoplasms. A prospective population-based study was conducted investigating whether a self-sampling human papillomavirus (HPV) test was feasible for under-users of Pap smear and factors associated with under-screening in Taiwan. Methods: Women not having Pap smear screening for > 5 years were invited to participate in this study. Invitation letters and educational brochures were mailed to 4% of randomly selected eligible women from Taoyuan City, Taiwan, and responders received an HPV self-sampling kit. Those with HPV-positive results were recalled for a Pap smear and colposcopy. Results: Between March 2010 and June 2012, 10,693 women were invited, 354 responded (3.3%), and 282 (2.6%) gave valid informed consent, answered the questionnaire, and submitted HPV samples. The median age of enrolled women was 48.1 years. Forty-seven women (16.7%) had a positive HPV test, and 14 women accepted further survey to find two CIN2+. Another two cases of CIN2+ were identified from a national registry database. The cost of direct mailing self-samplers was less than that done on request (from NT$434,866 to NT$164,229, response rate of 5% to 15%, respectively, versus NT$683,957 for detecting 1 CIN2+). Reasons for not attending screening included lack of time, embarrassment, assumed low risk, fear of positive results, and perceived potential pain. Among the responders, 90.8% found the method acceptable. Conclusion: Our study indicated that different approaches (e.g., direct mailing self-samplers to under-users and/or various educational interventions) must be explored to improve coverage in populations with culture characteristics similar to Taiwan.http://www.sciencedirect.com/science/article/pii/S0929664615003538cervical neoplasmshuman papillomavirusPap smearself-samplingscreening rate |
| spellingShingle | Hung-Hsueh Chou Huei-Jean Huang Hui-Hsin Cheng Chee-Jen Chang Lan-Yan Yang Chu-Chun Huang Wei-Yang Chang Swei Hsueh Angel Chao Chin-Jung Wang Yun-Hsin Tang Cheng-Tao Lin Jian-Tai Qiu Min-Yu Chen Chao-Yu Chen Kuan-Gen Huang Tzu-Chun Tsai Ting-Chang Chang Chyong-Huey Lai Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in Taiwan Journal of the Formosan Medical Association cervical neoplasms human papillomavirus Pap smear self-sampling screening rate |
| title | Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in Taiwan |
| title_full | Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in Taiwan |
| title_fullStr | Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in Taiwan |
| title_full_unstemmed | Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in Taiwan |
| title_short | Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in Taiwan |
| title_sort | self sampling hpv test in women not undergoing pap smear for more than 5 years and factors associated with under screening in taiwan |
| topic | cervical neoplasms human papillomavirus Pap smear self-sampling screening rate |
| url | http://www.sciencedirect.com/science/article/pii/S0929664615003538 |
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