Initial Experience on Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Staging of Lung Cancer
Background and objective It has been proven that endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) was a new minimally invasive method in the diagnosis for mediastinal lymph nodes. The aim of this study is to evaluate the diagnostic and staging yield of EBUS-TBNA for lung...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2010-05-01
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| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://www.lungca.org/index.php?journal=01&page=article&op=viewFile&path[]=10.3779%2Fj.issn.1009-3419.2010.05.11&path[]=1477 |
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| author | Ting YE Fu YANG Xiaoyang LUO Jianhua ZHOU Liqing FENG Bo PING Xian ZHOU Haiquan CHEN Hong HU Lei SHEN |
| author_facet | Ting YE Fu YANG Xiaoyang LUO Jianhua ZHOU Liqing FENG Bo PING Xian ZHOU Haiquan CHEN Hong HU Lei SHEN |
| author_sort | Ting YE |
| collection | DOAJ |
| description | Background and objective It has been proven that endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) was a new minimally invasive method in the diagnosis for mediastinal lymph nodes. The aim of this study is to evaluate the diagnostic and staging yield of EBUS-TBNA for lung cancer. Methods Seventy-five patients with tumors and enlarged mediastinal lymph nodes found by CT underwent the diagnosis by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) from April 1, 2009 to Febuary 8, 2010. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of EBUS-TBNA were evaluated. Results Seventy-five patients with 177 lymph node groups (2.4 groups in average) were studied. Histopathological samples were found in 49.33% patients and in 28.81% groups. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of EBUS-TBNA for diagnostic were 98.43%, 100.00%, 100.00%, 91.67% and 98.66%, respectively, in per patient analysis and were 95.10%, 100%, 100.00%, 82.93%, and 96.05%, respectively, in per group analysis, higher than CT examination (P < 0.05) expect for sensitivity (P=0.435). Staging changed in 19 (26.03%) patients after EBUS-TBNA. Conclusion EBUS-TBNA proved to be a safe procedure with a high yield for the diagnosis of lung cancer. |
| first_indexed | 2024-12-11T02:56:27Z |
| format | Article |
| id | doaj.art-f974a628bc2e45f9b7b20a3481db1c88 |
| institution | Directory Open Access Journal |
| issn | 1009-3419 1999-6187 |
| language | zho |
| last_indexed | 2024-12-11T02:56:27Z |
| publishDate | 2010-05-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj.art-f974a628bc2e45f9b7b20a3481db1c882022-12-22T01:23:09ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872010-05-01135438442Initial Experience on Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Staging of Lung CancerTing YEFu YANGXiaoyang LUOJianhua ZHOULiqing FENGBo PINGXian ZHOUHaiquan CHENHong HULei SHENBackground and objective It has been proven that endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) was a new minimally invasive method in the diagnosis for mediastinal lymph nodes. The aim of this study is to evaluate the diagnostic and staging yield of EBUS-TBNA for lung cancer. Methods Seventy-five patients with tumors and enlarged mediastinal lymph nodes found by CT underwent the diagnosis by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) from April 1, 2009 to Febuary 8, 2010. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of EBUS-TBNA were evaluated. Results Seventy-five patients with 177 lymph node groups (2.4 groups in average) were studied. Histopathological samples were found in 49.33% patients and in 28.81% groups. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of EBUS-TBNA for diagnostic were 98.43%, 100.00%, 100.00%, 91.67% and 98.66%, respectively, in per patient analysis and were 95.10%, 100%, 100.00%, 82.93%, and 96.05%, respectively, in per group analysis, higher than CT examination (P < 0.05) expect for sensitivity (P=0.435). Staging changed in 19 (26.03%) patients after EBUS-TBNA. Conclusion EBUS-TBNA proved to be a safe procedure with a high yield for the diagnosis of lung cancer.http://www.lungca.org/index.php?journal=01&page=article&op=viewFile&path[]=10.3779%2Fj.issn.1009-3419.2010.05.11&path[]=1477Endobronchial ultrasound-guided transbronchial needle aspirationLung neoplasmsDiagnosisStaging |
| spellingShingle | Ting YE Fu YANG Xiaoyang LUO Jianhua ZHOU Liqing FENG Bo PING Xian ZHOU Haiquan CHEN Hong HU Lei SHEN Initial Experience on Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Staging of Lung Cancer Chinese Journal of Lung Cancer Endobronchial ultrasound-guided transbronchial needle aspiration Lung neoplasms Diagnosis Staging |
| title | Initial Experience on Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Staging of Lung Cancer |
| title_full | Initial Experience on Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Staging of Lung Cancer |
| title_fullStr | Initial Experience on Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Staging of Lung Cancer |
| title_full_unstemmed | Initial Experience on Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Staging of Lung Cancer |
| title_short | Initial Experience on Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Staging of Lung Cancer |
| title_sort | initial experience on endobronchial ultrasound guided transbronchial needle aspiration in the diagnosis and staging of lung cancer |
| topic | Endobronchial ultrasound-guided transbronchial needle aspiration Lung neoplasms Diagnosis Staging |
| url | http://www.lungca.org/index.php?journal=01&page=article&op=viewFile&path[]=10.3779%2Fj.issn.1009-3419.2010.05.11&path[]=1477 |
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