Hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients; a single center study
Background: Abnormalities in calcium, phosphorous and parathyroid hormone (PTH) metabolisms are common in dialysis patients. Reaching target levels for these serologic factors and calcium × phosphorous products is recommended to minimize cardiovascular events. Objectives: The aim of this study was t...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2017-10-01
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| Series: | Journal of Nephropathology |
| Subjects: | |
| Online Access: | https://nephropathol.com/PDF/jnp-6-282.pdf |
| _version_ | 1797828017311973376 |
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| author | Mitra Naseri |
| author_facet | Mitra Naseri |
| author_sort | Mitra Naseri |
| collection | DOAJ |
| description | Background: Abnormalities in calcium, phosphorous and parathyroid hormone (PTH) metabolisms are common in dialysis patients. Reaching target levels for these serologic factors and calcium × phosphorous products is recommended to minimize cardiovascular events. Objectives: The aim of this study was to examine calcium, phosphorous and intact PTH (iPTH) abnormalities in a group of dialysis patients. Patients and Methods: Bone minerals status and iPTH levels were assessed in 46 dialysis patients aged 19-300 (165.2 ± 75.73) months. Low and high Ca dialysate solutions routinely were used for hemodialysis (63%) and peritoneal dialysis (30.4%) patients respectively. Comparisons between groups were performed with considering age (≤5, 6-10, and > 10 years), gender and modality of dialysis. Results: Serum calcium and corrected calcium levels were significantly higher in peritoneal dialysis (PD) patients. Hypoparathyroidism was the most frequent iPTH abnormality (58.7%). It was more prevalent in males. Hyperparathyroidism was more frequent in females. Conclusions: We found that hypoparathyroidism is the most prevalent PTH abnormality. We also noted that patients on peritoneal dialysis are more prone to develop this form of PTH abnormality. We found that phosphate control is better in peritoneal dialysis vs. hemodialysis cases. |
| first_indexed | 2024-04-09T12:57:43Z |
| format | Article |
| id | doaj.art-f975ec97423b4813ac1aefd8f3e4ad29 |
| institution | Directory Open Access Journal |
| issn | 2251-8363 2251-8819 |
| language | English |
| last_indexed | 2024-04-09T12:57:43Z |
| publishDate | 2017-10-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj.art-f975ec97423b4813ac1aefd8f3e4ad292023-05-13T11:31:11ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192017-10-016428228910.15171/jnp.2017.47jnp-20170615095200Hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients; a single center studyMitra Naseri0Department of Pediatric Nephrology, Mashhad University of Medical Sciences, Mashhad, IranBackground: Abnormalities in calcium, phosphorous and parathyroid hormone (PTH) metabolisms are common in dialysis patients. Reaching target levels for these serologic factors and calcium × phosphorous products is recommended to minimize cardiovascular events. Objectives: The aim of this study was to examine calcium, phosphorous and intact PTH (iPTH) abnormalities in a group of dialysis patients. Patients and Methods: Bone minerals status and iPTH levels were assessed in 46 dialysis patients aged 19-300 (165.2 ± 75.73) months. Low and high Ca dialysate solutions routinely were used for hemodialysis (63%) and peritoneal dialysis (30.4%) patients respectively. Comparisons between groups were performed with considering age (≤5, 6-10, and > 10 years), gender and modality of dialysis. Results: Serum calcium and corrected calcium levels were significantly higher in peritoneal dialysis (PD) patients. Hypoparathyroidism was the most frequent iPTH abnormality (58.7%). It was more prevalent in males. Hyperparathyroidism was more frequent in females. Conclusions: We found that hypoparathyroidism is the most prevalent PTH abnormality. We also noted that patients on peritoneal dialysis are more prone to develop this form of PTH abnormality. We found that phosphate control is better in peritoneal dialysis vs. hemodialysis cases.https://nephropathol.com/PDF/jnp-6-282.pdfckdhemodialysisperitoneal dialysispthparathormone |
| spellingShingle | Mitra Naseri Hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients; a single center study Journal of Nephropathology ckd hemodialysis peritoneal dialysis pth parathormone |
| title | Hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients; a single center study |
| title_full | Hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients; a single center study |
| title_fullStr | Hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients; a single center study |
| title_full_unstemmed | Hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients; a single center study |
| title_short | Hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients; a single center study |
| title_sort | hypoparathyroidism versus hyperparathyroidism in pediatric dialysis patients a single center study |
| topic | ckd hemodialysis peritoneal dialysis pth parathormone |
| url | https://nephropathol.com/PDF/jnp-6-282.pdf |
| work_keys_str_mv | AT mitranaseri hypoparathyroidismversushyperparathyroidisminpediatricdialysispatientsasinglecenterstudy |