Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies
(1) Background: In this narrative review, we focus on neural autoantibodies in patients with coronavirus disease 2019 (COVID-19) as a consequence of severe acute respiratory syndrome coronavirus type 2 infection and persisting symptoms of post-COVID-19 syndrome with a psychiatric presentation. (2) M...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Antibodies |
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| Online Access: | https://www.mdpi.com/2073-4468/12/3/49 |
| _version_ | 1797581542679117824 |
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| author | Niels Hansen |
| author_facet | Niels Hansen |
| author_sort | Niels Hansen |
| collection | DOAJ |
| description | (1) Background: In this narrative review, we focus on neural autoantibodies in patients with coronavirus disease 2019 (COVID-19) as a consequence of severe acute respiratory syndrome coronavirus type 2 infection and persisting symptoms of post-COVID-19 syndrome with a psychiatric presentation. (2) Methods: Our methods include using the PubMed database to search for appropriate articles. (3) Results: We first describe the phenomenon of the psychiatric manifestation of COVID-19 in acute and persistent forms, associated with neural autoantibodies, often attributable to encephalopathy or encephalitis. We discuss the spectrum of neural autoantibodies in neuropsychiatric patients affected by COVID-19 and post-COVID-19 syndrome. Evidence from our research suggests that it is highly likely that neural autoantibody production is facilitated by SARS-CoV-2 infection, and that more neuropsychiatric patients than control subjects will present neural autoantibodies. (4) Conclusions: These observations support the hypothesis that acute and persisting forms of COVID-19 promote autoimmune diseases. Our patients therefore require comprehensive evaluation to avoid overlooking such autoantibody-associated psychiatric disorders associated with COVID-19. |
| first_indexed | 2024-03-10T23:07:00Z |
| format | Article |
| id | doaj.art-f97952c9ce794bf0bf495dbf8de268b7 |
| institution | Directory Open Access Journal |
| issn | 2073-4468 |
| language | English |
| last_indexed | 2024-03-10T23:07:00Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibodies |
| spelling | doaj.art-f97952c9ce794bf0bf495dbf8de268b72023-11-19T09:18:22ZengMDPI AGAntibodies2073-44682023-07-011234910.3390/antib12030049Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural AutoantibodiesNiels Hansen0Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Von-Siebold-Str. 5, 37075 Göttingen, Germany(1) Background: In this narrative review, we focus on neural autoantibodies in patients with coronavirus disease 2019 (COVID-19) as a consequence of severe acute respiratory syndrome coronavirus type 2 infection and persisting symptoms of post-COVID-19 syndrome with a psychiatric presentation. (2) Methods: Our methods include using the PubMed database to search for appropriate articles. (3) Results: We first describe the phenomenon of the psychiatric manifestation of COVID-19 in acute and persistent forms, associated with neural autoantibodies, often attributable to encephalopathy or encephalitis. We discuss the spectrum of neural autoantibodies in neuropsychiatric patients affected by COVID-19 and post-COVID-19 syndrome. Evidence from our research suggests that it is highly likely that neural autoantibody production is facilitated by SARS-CoV-2 infection, and that more neuropsychiatric patients than control subjects will present neural autoantibodies. (4) Conclusions: These observations support the hypothesis that acute and persisting forms of COVID-19 promote autoimmune diseases. Our patients therefore require comprehensive evaluation to avoid overlooking such autoantibody-associated psychiatric disorders associated with COVID-19.https://www.mdpi.com/2073-4468/12/3/49neural autoantibodiesCOVID-19post-COVID syndromepsychiatryautoimmunity |
| spellingShingle | Niels Hansen Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies Antibodies neural autoantibodies COVID-19 post-COVID syndrome psychiatry autoimmunity |
| title | Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies |
| title_full | Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies |
| title_fullStr | Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies |
| title_full_unstemmed | Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies |
| title_short | Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies |
| title_sort | psychiatric symptoms in acute and persisting forms of covid 19 associated with neural autoantibodies |
| topic | neural autoantibodies COVID-19 post-COVID syndrome psychiatry autoimmunity |
| url | https://www.mdpi.com/2073-4468/12/3/49 |
| work_keys_str_mv | AT nielshansen psychiatricsymptomsinacuteandpersistingformsofcovid19associatedwithneuralautoantibodies |