Selective Sphingosine 1-Phosphate Receptor 1 Modulation Augments Thrombolysis of Low-Dose Tissue Plasminogen Activator Following Cerebrovascular Thrombosis

Selective Sphingosine 1-Phosphate Receptor 1 Modulation Augments Thrombolysis of Low-Dose Tissue Plasminogen Activator Following Cerebrovascular Thrombosis

BackgroundResults from our recent study demonstrate that sphingosine-1-phosphate receptor 1 (S1PR1) modulation improves microvascular hemodynamics after cerebrovascular thrombosis. This study was to determine the microvascular hemodynamic effects of a sub-thrombolytic dose of tPA combined with a sel...

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Bibliographic Details
Main Authors:	Han-Dong Li, Ran Li, Ying Kong, Wenyan Zhang, Caiyun Qi, Dan Wang, Hongying Hao, Qiang Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Series:	Frontiers in Immunology
Subjects:	two-photon microscopy tPA thrombolysis microcirculation ischemic stroke
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.801727/full

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