Combined Visualization of Nigrosome-1 and Neuromelanin in the Substantia Nigra Using 3T MRI for the Differential Diagnosis of Essential Tremor and de novo Parkinson's Disease

Combined Visualization of Nigrosome-1 and Neuromelanin in the Substantia Nigra Using 3T MRI for the Differential Diagnosis of Essential Tremor and de novo Parkinson's Disease

Differentiating early-stage Parkinson's disease (PD) from essential tremor (ET) remains challenging. In the current study, we aimed to evaluate whether visual analyses of neuromelanin-sensitive magnetic resonance imaging (NM-MRI) combined with nigrosome-1 (N1) imaging using quantitative suscept...

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Bibliographic Details
Main Authors: Lirong Jin, Jian Wang, Changpeng Wang, Danlan Lian, Ying Zhou, Yong Zhang, Minzhi Lv, Yuanfang Li, Zhen Huang, Xiaoqin Cheng, Guoqiang Fei, Kai Liu, Mengsu Zeng, Chunjiu Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
essential tremor
neuromelanin
nigrosome-1
QSM
substantia nigra
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00100/full

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