Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial
Background. Conventional mechanical debridement alone cannot eliminate bacteria and their products from periodontal pockets. Adjunctive therapies improve tissue healing through detoxification and bactericidal effects. Photodynamic therapy (PDT) is a non-invasive treatment procedure that involves the...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2020-09-01
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| Series: | Journal of Dental Research, Dental Clinics, Dental Prospects |
| Subjects: | |
| Online Access: | https://joddd.tbzmed.ac.ir/PDF/joddd-14-191.pdf |
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| author | Sahana Mallineni Sreenivas Nagarakanti Sumanth Gunupati Ramesh Reddy BV Mahaboob V Shaik Vijay K Chava |
| author_facet | Sahana Mallineni Sreenivas Nagarakanti Sumanth Gunupati Ramesh Reddy BV Mahaboob V Shaik Vijay K Chava |
| author_sort | Sahana Mallineni |
| collection | DOAJ |
| description | Background. Conventional mechanical debridement alone cannot eliminate bacteria and their products from periodontal pockets. Adjunctive therapies improve tissue healing through detoxification and bactericidal effects. Photodynamic therapy (PDT) is a non-invasive treatment procedure that involves the use of a dye as a photosensitizer to attach to the target cell and be activated by a photon of an appropriate wavelength. This study aimed to assess the effectiveness of PDT in treating periodontitis as an adjunct to scaling and root planing. Methods. Fifteen subjects with chronic periodontitis were treated randomly with scaling and root planing (SRP), followed by a single PDT (test) or SRP (control) episode alone. Full-mouth plaque index (PI), sulcus bleeding index (SBI), probing depth (PD), and clinical attachment level (CAL) were assessed at baseline and 1-month and 3-month intervals. Microbiological evaluation of Porphyromonas gingivalis (Pg) in subgingival plaque samples was performed using a commercially available real-time polymerase chain reaction. Results. The results revealed a significant difference in PI, SBI, PD, CAL, and microbiological parameters between the groups one and three months after treatment. Conclusion. A combination of PDT and SRP gave rise to a significant improvement in clinical and microbiological parameters in patients with chronic periodontitis. |
| first_indexed | 2024-12-12T07:17:50Z |
| format | Article |
| id | doaj.art-f97b3ae2c86a4f478ffe23eed92337fc |
| institution | Directory Open Access Journal |
| issn | 2008-210X 2008-2118 |
| language | English |
| last_indexed | 2024-12-12T07:17:50Z |
| publishDate | 2020-09-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dental Research, Dental Clinics, Dental Prospects |
| spelling | doaj.art-f97b3ae2c86a4f478ffe23eed92337fc2022-12-22T00:33:29ZengTabriz University of Medical SciencesJournal of Dental Research, Dental Clinics, Dental Prospects2008-210X2008-21182020-09-0114319119710.34172/joddd.2020.030joddd-27751Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trialSahana Mallineni0Sreenivas Nagarakanti1Sumanth Gunupati2Ramesh Reddy BV3Mahaboob V Shaik4Vijay K Chava5Department of Periodontology, Narayana Dental College & Hospital, Nellore, IndiaDepartment of Periodontology, Narayana Dental College & Hospital, Nellore, IndiaDepartment of Periodontology, Narayana Dental College & Hospital, Nellore, IndiaDepartment of Periodontology, Narayana Dental College & Hospital, Nellore, IndiaDepartment of Genetics, Advanced Research Centre, Narayana Medical College & Hospital, Nellore, IndiaDepartment of Periodontology, Narayana Dental College & Hospital, Nellore, IndiaBackground. Conventional mechanical debridement alone cannot eliminate bacteria and their products from periodontal pockets. Adjunctive therapies improve tissue healing through detoxification and bactericidal effects. Photodynamic therapy (PDT) is a non-invasive treatment procedure that involves the use of a dye as a photosensitizer to attach to the target cell and be activated by a photon of an appropriate wavelength. This study aimed to assess the effectiveness of PDT in treating periodontitis as an adjunct to scaling and root planing. Methods. Fifteen subjects with chronic periodontitis were treated randomly with scaling and root planing (SRP), followed by a single PDT (test) or SRP (control) episode alone. Full-mouth plaque index (PI), sulcus bleeding index (SBI), probing depth (PD), and clinical attachment level (CAL) were assessed at baseline and 1-month and 3-month intervals. Microbiological evaluation of Porphyromonas gingivalis (Pg) in subgingival plaque samples was performed using a commercially available real-time polymerase chain reaction. Results. The results revealed a significant difference in PI, SBI, PD, CAL, and microbiological parameters between the groups one and three months after treatment. Conclusion. A combination of PDT and SRP gave rise to a significant improvement in clinical and microbiological parameters in patients with chronic periodontitis.https://joddd.tbzmed.ac.ir/PDF/joddd-14-191.pdfchronic periodontitisphotodynamic therapyhotosensitizing agentspolymerase chain reactionporphyromonas gingivalis |
| spellingShingle | Sahana Mallineni Sreenivas Nagarakanti Sumanth Gunupati Ramesh Reddy BV Mahaboob V Shaik Vijay K Chava Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial Journal of Dental Research, Dental Clinics, Dental Prospects chronic periodontitis photodynamic therapy hotosensitizing agents polymerase chain reaction porphyromonas gingivalis |
| title | Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial |
| title_full | Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial |
| title_fullStr | Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial |
| title_full_unstemmed | Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial |
| title_short | Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial |
| title_sort | clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis a randomized clinical trial |
| topic | chronic periodontitis photodynamic therapy hotosensitizing agents polymerase chain reaction porphyromonas gingivalis |
| url | https://joddd.tbzmed.ac.ir/PDF/joddd-14-191.pdf |
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