Understanding Post-Sepsis Syndrome: How Can Clinicians Help?
Elisabeth C van der Slikke,1 Lise FE Beumeler,2,3 Madlene Holmqvist,4 Adam Linder,4 Robert T Mankowski,5 Hjalmar R Bouma1,6 1Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, the Netherlands; 2Department of Intensive Ca...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-09-01
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| Series: | Infection and Drug Resistance |
| Subjects: | |
| Online Access: | https://www.dovepress.com/understanding-post-sepsis-syndrome-how-can-clinicians-help-peer-reviewed-fulltext-article-IDR |
| _version_ | 1797669478877626368 |
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| author | van der Slikke EC Beumeler LFE Holmqvist M Linder A Mankowski RT Bouma HR |
| author_facet | van der Slikke EC Beumeler LFE Holmqvist M Linder A Mankowski RT Bouma HR |
| author_sort | van der Slikke EC |
| collection | DOAJ |
| description | Elisabeth C van der Slikke,1 Lise FE Beumeler,2,3 Madlene Holmqvist,4 Adam Linder,4 Robert T Mankowski,5 Hjalmar R Bouma1,6 1Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, the Netherlands; 2Department of Intensive Care, Medical Centre Leeuwarden, Leeuwarden, 8934AD, the Netherlands; 3Department of Sustainable Health, Campus Fryslân, University of Groningen, Groningen, 8911 CE, the Netherlands; 4Department of Infection Medicine, Skåne University Hospital Lund, Lund, 221 84, Sweden; 5Department of Physiology and Aging, University of Florida, Gainesville, FL, 32610, USA; 6Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, the NetherlandsCorrespondence: Hjalmar R Bouma, Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, P.O. Box 30.001, EB70, Groningen, 9700 RB, the Netherlands, Tel +31 (0) 50 361 7870, Email h.r.bouma@umcg.nlAbstract: Sepsis is a global health challenge, with over 49 million cases annually. Recent medical advancements have increased in-hospital survival rates to approximately 80%, but the escalating incidence of sepsis, owing to an ageing population, rise in chronic diseases, and antibiotic resistance, have also increased the number of sepsis survivors. Subsequently, there is a growing prevalence of “post-sepsis syndrome” (PSS). This syndrome includes long-term physical, medical, cognitive, and psychological issues after recovering from sepsis. PSS puts survivors at risk for hospital readmission and is associated with a reduction in health- and life span, both at short and long term, after hospital discharge. Comprehensive understanding of PSS symptoms and causative factors is vital for developing optimal care for sepsis survivors, a task of prime importance for clinicians. This review aims to elucidate our current knowledge of PSS and its relevance in enhancing post-sepsis care provided by clinicians.Keywords: post-sepsis syndrome, sepsis, long-term outcome |
| first_indexed | 2024-03-11T20:44:58Z |
| format | Article |
| id | doaj.art-f97c18b5a1e842cfbeadbd055c2363f9 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-03-11T20:44:58Z |
| publishDate | 2023-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-f97c18b5a1e842cfbeadbd055c2363f92023-10-01T18:14:19ZengDove Medical PressInfection and Drug Resistance1178-69732023-09-01Volume 166493651187049Understanding Post-Sepsis Syndrome: How Can Clinicians Help?van der Slikke ECBeumeler LFEHolmqvist MLinder AMankowski RTBouma HRElisabeth C van der Slikke,1 Lise FE Beumeler,2,3 Madlene Holmqvist,4 Adam Linder,4 Robert T Mankowski,5 Hjalmar R Bouma1,6 1Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, the Netherlands; 2Department of Intensive Care, Medical Centre Leeuwarden, Leeuwarden, 8934AD, the Netherlands; 3Department of Sustainable Health, Campus Fryslân, University of Groningen, Groningen, 8911 CE, the Netherlands; 4Department of Infection Medicine, Skåne University Hospital Lund, Lund, 221 84, Sweden; 5Department of Physiology and Aging, University of Florida, Gainesville, FL, 32610, USA; 6Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, the NetherlandsCorrespondence: Hjalmar R Bouma, Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, P.O. Box 30.001, EB70, Groningen, 9700 RB, the Netherlands, Tel +31 (0) 50 361 7870, Email h.r.bouma@umcg.nlAbstract: Sepsis is a global health challenge, with over 49 million cases annually. Recent medical advancements have increased in-hospital survival rates to approximately 80%, but the escalating incidence of sepsis, owing to an ageing population, rise in chronic diseases, and antibiotic resistance, have also increased the number of sepsis survivors. Subsequently, there is a growing prevalence of “post-sepsis syndrome” (PSS). This syndrome includes long-term physical, medical, cognitive, and psychological issues after recovering from sepsis. PSS puts survivors at risk for hospital readmission and is associated with a reduction in health- and life span, both at short and long term, after hospital discharge. Comprehensive understanding of PSS symptoms and causative factors is vital for developing optimal care for sepsis survivors, a task of prime importance for clinicians. This review aims to elucidate our current knowledge of PSS and its relevance in enhancing post-sepsis care provided by clinicians.Keywords: post-sepsis syndrome, sepsis, long-term outcomehttps://www.dovepress.com/understanding-post-sepsis-syndrome-how-can-clinicians-help-peer-reviewed-fulltext-article-IDRpost-sepsis syndromesepsislong-term outcome |
| spellingShingle | van der Slikke EC Beumeler LFE Holmqvist M Linder A Mankowski RT Bouma HR Understanding Post-Sepsis Syndrome: How Can Clinicians Help? Infection and Drug Resistance post-sepsis syndrome sepsis long-term outcome |
| title | Understanding Post-Sepsis Syndrome: How Can Clinicians Help? |
| title_full | Understanding Post-Sepsis Syndrome: How Can Clinicians Help? |
| title_fullStr | Understanding Post-Sepsis Syndrome: How Can Clinicians Help? |
| title_full_unstemmed | Understanding Post-Sepsis Syndrome: How Can Clinicians Help? |
| title_short | Understanding Post-Sepsis Syndrome: How Can Clinicians Help? |
| title_sort | understanding post sepsis syndrome how can clinicians help |
| topic | post-sepsis syndrome sepsis long-term outcome |
| url | https://www.dovepress.com/understanding-post-sepsis-syndrome-how-can-clinicians-help-peer-reviewed-fulltext-article-IDR |
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