Antibiotics in acute appendicitis. When and how? A general review
Introduction: An increasing interest exits towards the use of antibiotics in the treatment of uncomplicated acute appendicitis.Discussion: For a long period of time, surgery was the only treatment for acute appendicitis. Due to recent research in the etiology of acute appendicitis which seems to be...
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Editura Universitara Carol Davila
2019-05-01
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| Colecção: | Journal of Surgical Sciences |
| Assuntos: | |
| Acesso em linha: | http://journalofsurgicalsciences.com/index.php/jss/article/view/258 |
| _version_ | 1828918025318825984 |
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| author | L. Alecu C. Niţipir Iulian Slavu V. Braga D. Mihăilă A. Tulin |
| author_facet | L. Alecu C. Niţipir Iulian Slavu V. Braga D. Mihăilă A. Tulin |
| author_sort | L. Alecu |
| collection | DOAJ |
| description | Introduction: An increasing interest exits towards the use of antibiotics in the treatment of uncomplicated acute appendicitis.Discussion: For a long period of time, surgery was the only treatment for acute appendicitis. Due to recent research in the etiology of acute appendicitis which seems to be driven by intraluminal bacterial proliferation, new data suggests that for non-perforated appendicitis confirmed with the help of CT, antibiotics may play a central role in the treatment. As relapse rates amount in some cases to only 5% after antibiotic treament, a discussion is required regarding the risks of interval appendectomy and its use. The debate regarding the optimal antibiotic course is on-going as some surgeons advocate for amoxicillin/clavulanic while others, due to acquired resistance recommend Ertapenem.Conclusion: Selective antibiotic treatment for selected forms of acute appendicitis, uncomplicated without perforation is safe and has a relatively low complication rate. However, certain mentions must be made: surgery must not be delayed if failure of antibiotics exists as it can lead to higher rates of peritonitis. Close clinical surveillance is of utmost importance |
| first_indexed | 2024-12-13T21:02:08Z |
| format | Article |
| id | doaj.art-f97c91e7af1e4c5fa26c7d7408ae6fb8 |
| institution | Directory Open Access Journal |
| issn | 2360-3038 2457-5364 |
| language | English |
| last_indexed | 2024-12-13T21:02:08Z |
| publishDate | 2019-05-01 |
| publisher | Editura Universitara Carol Davila |
| record_format | Article |
| series | Journal of Surgical Sciences |
| spelling | doaj.art-f97c91e7af1e4c5fa26c7d7408ae6fb82022-12-21T23:31:34ZengEditura Universitara Carol DavilaJournal of Surgical Sciences2360-30382457-53642019-05-0161303310.33695/jss.v6i1.258258Antibiotics in acute appendicitis. When and how? A general reviewL. Alecu0C. Niţipir1Iulian Slavu2V. Braga3D. Mihăilă4A. Tulin5General Surgery Clinic, Prof. Dr.”Agrippa Ionescu” Emergency Clinical Hospital, Bucharest, RomaniaEmergency Clinical Hospital Elias, Bucharest, RomaniaSp Clinic de Urgenta BucurestiGeneral Surgery Clinic, Emergency Clinical Hospital, Bucharest, RomaniaGeneral Surgery Clinic, Prof. Dr.”Agrippa Ionescu” Emergency Clinical Hospital, Bucharest, RomaniaClinic of General Surgery ”Prof. Dr. Agrippa Ionescu” Emergency Hospital, Bucharest, RomaniaIntroduction: An increasing interest exits towards the use of antibiotics in the treatment of uncomplicated acute appendicitis.Discussion: For a long period of time, surgery was the only treatment for acute appendicitis. Due to recent research in the etiology of acute appendicitis which seems to be driven by intraluminal bacterial proliferation, new data suggests that for non-perforated appendicitis confirmed with the help of CT, antibiotics may play a central role in the treatment. As relapse rates amount in some cases to only 5% after antibiotic treament, a discussion is required regarding the risks of interval appendectomy and its use. The debate regarding the optimal antibiotic course is on-going as some surgeons advocate for amoxicillin/clavulanic while others, due to acquired resistance recommend Ertapenem.Conclusion: Selective antibiotic treatment for selected forms of acute appendicitis, uncomplicated without perforation is safe and has a relatively low complication rate. However, certain mentions must be made: surgery must not be delayed if failure of antibiotics exists as it can lead to higher rates of peritonitis. Close clinical surveillance is of utmost importancehttp://journalofsurgicalsciences.com/index.php/jss/article/view/258antibiotic treatment, acute appendicitis |
| spellingShingle | L. Alecu C. Niţipir Iulian Slavu V. Braga D. Mihăilă A. Tulin Antibiotics in acute appendicitis. When and how? A general review Journal of Surgical Sciences antibiotic treatment, acute appendicitis |
| title | Antibiotics in acute appendicitis. When and how? A general review |
| title_full | Antibiotics in acute appendicitis. When and how? A general review |
| title_fullStr | Antibiotics in acute appendicitis. When and how? A general review |
| title_full_unstemmed | Antibiotics in acute appendicitis. When and how? A general review |
| title_short | Antibiotics in acute appendicitis. When and how? A general review |
| title_sort | antibiotics in acute appendicitis when and how a general review |
| topic | antibiotic treatment, acute appendicitis |
| url | http://journalofsurgicalsciences.com/index.php/jss/article/view/258 |
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