Efficacy of different types of phototherapy units on neonatal hyperbilirubinemia

Context: Phototherapy is the mainstay of treatment for about 3% of neonates in India who develop significant jaundice in phototherapy range. New devices have been introduced in the market over the past few years. Aims: To compare the efficacy of three types of phototherapy machines, namely Blue and...

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Main Authors: Krishna M Adhikari, Sheila S Mathai, Sathya M Moorthy, Naveen Chawla, Sandeep Dhingra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Marine Medical Society
Subjects:
Online Access:http://www.marinemedicalsociety.in/article.asp?issn=0975-3605;year=2017;volume=19;issue=2;spage=99;epage=102;aulast=Adhikari
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author Krishna M Adhikari
Sheila S Mathai
Sathya M Moorthy
Naveen Chawla
Sandeep Dhingra
author_facet Krishna M Adhikari
Sheila S Mathai
Sathya M Moorthy
Naveen Chawla
Sandeep Dhingra
author_sort Krishna M Adhikari
collection DOAJ
description Context: Phototherapy is the mainstay of treatment for about 3% of neonates in India who develop significant jaundice in phototherapy range. New devices have been introduced in the market over the past few years. Aims: To compare the efficacy of three types of phototherapy machines, namely Blue and White, Compact Fluorescent Lamp, and Light Emitting Diode type. Settings and Design: A non-randomized prospective interventional study conducted in a tertiary care hospital of Western India. Material and Methods: Ninety neonates with phototherapy range hyperbilirubinemia were assigned into three groups of 30 neonates each to receive phototherapy using one of the three types of phototherapy machines. Need for exchange transfusion, total serum bilirubin (TSB) at 24 hours post-phototherapy and side effect profile were recorded. Decision to stop phototherapy was based on acceptable reduction of serum bilirubin to below phototherapy range. Statistical analysis used: Medcalc® Version 11.4.2.0 Software was utilised. Comparison of mean TSB was done using one way ANOVA. P-value of <0.05 was considered significant. Results: Baseline parameters, TSB at 24 hour post-phototherapy and at the point of stopping phototherapy in the three groups was not significantly different. None of the babies required exchange transfusion or stopping of therapy. Transient rash was the most commonly observed side effect. Conclusions: The three types of phototherapy equipment studied were comparable in efficacy as measured by need for exchange transfusion and mean TSB values at 24 hrs post-phototherapy. The side effect profile was similar and was not significant enough to stop phototherapy.
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spelling doaj.art-f97caa278d6249469f503ca66af0bd4d2022-12-22T01:06:33ZengWolters Kluwer Medknow PublicationsJournal of Marine Medical Society0975-36052017-01-011929910210.4103/jmms.jmms_59_17Efficacy of different types of phototherapy units on neonatal hyperbilirubinemiaKrishna M AdhikariSheila S MathaiSathya M MoorthyNaveen ChawlaSandeep DhingraContext: Phototherapy is the mainstay of treatment for about 3% of neonates in India who develop significant jaundice in phototherapy range. New devices have been introduced in the market over the past few years. Aims: To compare the efficacy of three types of phototherapy machines, namely Blue and White, Compact Fluorescent Lamp, and Light Emitting Diode type. Settings and Design: A non-randomized prospective interventional study conducted in a tertiary care hospital of Western India. Material and Methods: Ninety neonates with phototherapy range hyperbilirubinemia were assigned into three groups of 30 neonates each to receive phototherapy using one of the three types of phototherapy machines. Need for exchange transfusion, total serum bilirubin (TSB) at 24 hours post-phototherapy and side effect profile were recorded. Decision to stop phototherapy was based on acceptable reduction of serum bilirubin to below phototherapy range. Statistical analysis used: Medcalc® Version 11.4.2.0 Software was utilised. Comparison of mean TSB was done using one way ANOVA. P-value of <0.05 was considered significant. Results: Baseline parameters, TSB at 24 hour post-phototherapy and at the point of stopping phototherapy in the three groups was not significantly different. None of the babies required exchange transfusion or stopping of therapy. Transient rash was the most commonly observed side effect. Conclusions: The three types of phototherapy equipment studied were comparable in efficacy as measured by need for exchange transfusion and mean TSB values at 24 hrs post-phototherapy. The side effect profile was similar and was not significant enough to stop phototherapy.http://www.marinemedicalsociety.in/article.asp?issn=0975-3605;year=2017;volume=19;issue=2;spage=99;epage=102;aulast=AdhikariHyperbilirubinemiaPhototherapyNewborn jaundice
spellingShingle Krishna M Adhikari
Sheila S Mathai
Sathya M Moorthy
Naveen Chawla
Sandeep Dhingra
Efficacy of different types of phototherapy units on neonatal hyperbilirubinemia
Journal of Marine Medical Society
Hyperbilirubinemia
Phototherapy
Newborn jaundice
title Efficacy of different types of phototherapy units on neonatal hyperbilirubinemia
title_full Efficacy of different types of phototherapy units on neonatal hyperbilirubinemia
title_fullStr Efficacy of different types of phototherapy units on neonatal hyperbilirubinemia
title_full_unstemmed Efficacy of different types of phototherapy units on neonatal hyperbilirubinemia
title_short Efficacy of different types of phototherapy units on neonatal hyperbilirubinemia
title_sort efficacy of different types of phototherapy units on neonatal hyperbilirubinemia
topic Hyperbilirubinemia
Phototherapy
Newborn jaundice
url http://www.marinemedicalsociety.in/article.asp?issn=0975-3605;year=2017;volume=19;issue=2;spage=99;epage=102;aulast=Adhikari
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