Correlation between Microvascular Damage and Internal Organ Involvement in Scleroderma: Focus on Lung Damage and Endothelial Dysfunction

Correlation between Microvascular Damage and Internal Organ Involvement in Scleroderma: Focus on Lung Damage and Endothelial Dysfunction

Background. Systemic sclerosis (SSc) is an incurable connective tissue disease characterized by decreased peripheral blood perfusion due to microvascular damage and skin thickening/hardening. The microcirculation deficit is typically secondary to structural vessel damage, which can be assessed morph...

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Bibliographic Details
Main Authors: Mario D’Oria, Ilaria Gandin, Pozzan Riccardo, Michael Hughes, Sandro Lepidi, Francesco Salton, Paola Confalonieri, Marco Confalonieri, Stefano Tavano, Barbara Ruaro
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Diagnostics
Subjects:
systemic sclerosis (SSc)
peripheral blood perfusion (PBP)
dermal thickness (DT)
lung impairments
Online Access:https://www.mdpi.com/2075-4418/13/1/55

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