A Polytetrafluoroethylene (PTFE) and Nano-Al<sub>2</sub>O<sub>3</sub> Based Composite Coating with a Bacteriostatic Effect against <i>E. coli</i> and Low Cytotoxicity
The problem of bacterial contamination through surfaces is important for the food industry. In this regard, there is a growing interest in new coatings based on nanoparticles that can provide a long-term antibacterial effect. Aluminum oxide nanoparticles are a good candidate for such coatings due to...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/21/4764 |
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| author | Dmitriy E. Burmistrov Dmitriy A. Serov Aleksander V. Simakin Ilya V. Baimler Oleg V. Uvarov Sergey V. Gudkov |
| author_facet | Dmitriy E. Burmistrov Dmitriy A. Serov Aleksander V. Simakin Ilya V. Baimler Oleg V. Uvarov Sergey V. Gudkov |
| author_sort | Dmitriy E. Burmistrov |
| collection | DOAJ |
| description | The problem of bacterial contamination through surfaces is important for the food industry. In this regard, there is a growing interest in new coatings based on nanoparticles that can provide a long-term antibacterial effect. Aluminum oxide nanoparticles are a good candidate for such coatings due to their availability and good biocompatibility. In this study, a coating containing aluminum oxide nanoparticles was produced using polytetrafluoroethylene as a polymer matrix—a polymer that exhibits excellent mechanical and physicochemical properties and it is not toxic. The obtained coatings based on “liquid Teflon” containing various concentrations of nanoparticles (0.001–0.1 wt%) prevented the bacterial growth, and they did not exhibit a cytotoxicity on animal cells in vitro. Such coatings are designed not only to provide an antibacterial surface effect, but also to eliminate micro damages on surfaces that inevitably occur in the process of food production. |
| first_indexed | 2024-03-09T18:43:39Z |
| format | Article |
| id | doaj.art-f9802500c4d647528cbe350160e3e07c |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T18:43:39Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-f9802500c4d647528cbe350160e3e07c2023-11-24T06:31:32ZengMDPI AGPolymers2073-43602022-11-011421476410.3390/polym14214764A Polytetrafluoroethylene (PTFE) and Nano-Al<sub>2</sub>O<sub>3</sub> Based Composite Coating with a Bacteriostatic Effect against <i>E. coli</i> and Low CytotoxicityDmitriy E. Burmistrov0Dmitriy A. Serov1Aleksander V. Simakin2Ilya V. Baimler3Oleg V. Uvarov4Sergey V. Gudkov5Prokhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilova St., 119991 Moscow, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilova St., 119991 Moscow, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilova St., 119991 Moscow, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilova St., 119991 Moscow, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilova St., 119991 Moscow, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilova St., 119991 Moscow, RussiaThe problem of bacterial contamination through surfaces is important for the food industry. In this regard, there is a growing interest in new coatings based on nanoparticles that can provide a long-term antibacterial effect. Aluminum oxide nanoparticles are a good candidate for such coatings due to their availability and good biocompatibility. In this study, a coating containing aluminum oxide nanoparticles was produced using polytetrafluoroethylene as a polymer matrix—a polymer that exhibits excellent mechanical and physicochemical properties and it is not toxic. The obtained coatings based on “liquid Teflon” containing various concentrations of nanoparticles (0.001–0.1 wt%) prevented the bacterial growth, and they did not exhibit a cytotoxicity on animal cells in vitro. Such coatings are designed not only to provide an antibacterial surface effect, but also to eliminate micro damages on surfaces that inevitably occur in the process of food production.https://www.mdpi.com/2073-4360/14/21/4764aluminum oxidepolytetrafluoroethylene (PTFE)nanoparticlescompositebiocompatibilityantibacterial coating |
| spellingShingle | Dmitriy E. Burmistrov Dmitriy A. Serov Aleksander V. Simakin Ilya V. Baimler Oleg V. Uvarov Sergey V. Gudkov A Polytetrafluoroethylene (PTFE) and Nano-Al<sub>2</sub>O<sub>3</sub> Based Composite Coating with a Bacteriostatic Effect against <i>E. coli</i> and Low Cytotoxicity Polymers aluminum oxide polytetrafluoroethylene (PTFE) nanoparticles composite biocompatibility antibacterial coating |
| title | A Polytetrafluoroethylene (PTFE) and Nano-Al<sub>2</sub>O<sub>3</sub> Based Composite Coating with a Bacteriostatic Effect against <i>E. coli</i> and Low Cytotoxicity |
| title_full | A Polytetrafluoroethylene (PTFE) and Nano-Al<sub>2</sub>O<sub>3</sub> Based Composite Coating with a Bacteriostatic Effect against <i>E. coli</i> and Low Cytotoxicity |
| title_fullStr | A Polytetrafluoroethylene (PTFE) and Nano-Al<sub>2</sub>O<sub>3</sub> Based Composite Coating with a Bacteriostatic Effect against <i>E. coli</i> and Low Cytotoxicity |
| title_full_unstemmed | A Polytetrafluoroethylene (PTFE) and Nano-Al<sub>2</sub>O<sub>3</sub> Based Composite Coating with a Bacteriostatic Effect against <i>E. coli</i> and Low Cytotoxicity |
| title_short | A Polytetrafluoroethylene (PTFE) and Nano-Al<sub>2</sub>O<sub>3</sub> Based Composite Coating with a Bacteriostatic Effect against <i>E. coli</i> and Low Cytotoxicity |
| title_sort | polytetrafluoroethylene ptfe and nano al sub 2 sub o sub 3 sub based composite coating with a bacteriostatic effect against i e coli i and low cytotoxicity |
| topic | aluminum oxide polytetrafluoroethylene (PTFE) nanoparticles composite biocompatibility antibacterial coating |
| url | https://www.mdpi.com/2073-4360/14/21/4764 |
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