Favorable outcomes of NPM1mut AML patients are due to transcriptional inactivation of FOXM1, presenting a new target to overcome chemoresistance
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-08-01
|
Series: | Blood Cancer Journal |
Online Access: | https://doi.org/10.1038/s41408-023-00898-4 |
_version_ | 1797578064839835648 |
---|---|
author | I. Khan A. Kaempf S. Raghuwanshi M. Chesnokov X. Zhang Z. Wang A. Domling J. W. Tyner C. Camacho A. L. Gartel |
author_facet | I. Khan A. Kaempf S. Raghuwanshi M. Chesnokov X. Zhang Z. Wang A. Domling J. W. Tyner C. Camacho A. L. Gartel |
author_sort | I. Khan |
collection | DOAJ |
first_indexed | 2024-03-10T22:16:56Z |
format | Article |
id | doaj.art-f9819aaa5aff4a02970deed6557e6a42 |
institution | Directory Open Access Journal |
issn | 2044-5385 |
language | English |
last_indexed | 2024-03-10T22:16:56Z |
publishDate | 2023-08-01 |
publisher | Nature Publishing Group |
record_format | Article |
series | Blood Cancer Journal |
spelling | doaj.art-f9819aaa5aff4a02970deed6557e6a422023-11-19T12:25:32ZengNature Publishing GroupBlood Cancer Journal2044-53852023-08-011311510.1038/s41408-023-00898-4Favorable outcomes of NPM1mut AML patients are due to transcriptional inactivation of FOXM1, presenting a new target to overcome chemoresistanceI. Khan0A. Kaempf1S. Raghuwanshi2M. Chesnokov3X. Zhang4Z. Wang5A. Domling6J. W. Tyner7C. Camacho8A. L. Gartel9University of Illinois at Chicago, Department of MedicineOHSU Knight Cancer Institute, School of MedicineUniversity of Illinois at Chicago, Department of MedicineCentro Nacional de Investigaciones Oncológicas (CNIO)University of Illinois at Chicago, Department of MedicineThe Czech Advanced Technology and Research Institute (CATRIN) of Palacký UniversityThe Czech Advanced Technology and Research Institute (CATRIN) of Palacký UniversityOHSU Knight Cancer Institute, School of MedicineComputational and Systems Biology, University of PittsburghUniversity of Illinois at Chicago, Department of Medicinehttps://doi.org/10.1038/s41408-023-00898-4 |
spellingShingle | I. Khan A. Kaempf S. Raghuwanshi M. Chesnokov X. Zhang Z. Wang A. Domling J. W. Tyner C. Camacho A. L. Gartel Favorable outcomes of NPM1mut AML patients are due to transcriptional inactivation of FOXM1, presenting a new target to overcome chemoresistance Blood Cancer Journal |
title | Favorable outcomes of NPM1mut AML patients are due to transcriptional inactivation of FOXM1, presenting a new target to overcome chemoresistance |
title_full | Favorable outcomes of NPM1mut AML patients are due to transcriptional inactivation of FOXM1, presenting a new target to overcome chemoresistance |
title_fullStr | Favorable outcomes of NPM1mut AML patients are due to transcriptional inactivation of FOXM1, presenting a new target to overcome chemoresistance |
title_full_unstemmed | Favorable outcomes of NPM1mut AML patients are due to transcriptional inactivation of FOXM1, presenting a new target to overcome chemoresistance |
title_short | Favorable outcomes of NPM1mut AML patients are due to transcriptional inactivation of FOXM1, presenting a new target to overcome chemoresistance |
title_sort | favorable outcomes of npm1mut aml patients are due to transcriptional inactivation of foxm1 presenting a new target to overcome chemoresistance |
url | https://doi.org/10.1038/s41408-023-00898-4 |
work_keys_str_mv | AT ikhan favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT akaempf favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT sraghuwanshi favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT mchesnokov favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT xzhang favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT zwang favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT adomling favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT jwtyner favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT ccamacho favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance AT algartel favorableoutcomesofnpm1mutamlpatientsareduetotranscriptionalinactivationoffoxm1presentinganewtargettoovercomechemoresistance |