Molecular characterization of rifabutin-resistance in refractory Helicobacter pylori infection in Taiwan

Molecular characterization of rifabutin-resistance in refractory Helicobacter pylori infection in Taiwan

Objectives: To explore the molecular characteristics of rpoB, encoding β-subunit of DNA-directed RNA polymerase, and unravel the link to rifabutin-resistance in patients with refractory Helicobacter pylori infection. Methods: From January 2018-March 2021, a total of 1590 patients were screened for e...

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Main Authors: Chia-Jung Kuo, Ngoc-Niem Bui, Jun-Nong Ke, Cheng-Yu Lin, Wey-Ran Lin, Ming-Ling Chang, Hui-Yu Wu, Mei-Zi Huang, Cheng-Hsun Chiu, Cheng-Tang Chiu, Chih-Ho Lai
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:International Journal of Infectious Diseases
Subjects:
Helicobacter pylori
Refractory infection
Rifabutin-resistance
RpoB
Mutation
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223007622

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