Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virus
Abstract Inflammatory pseudotumour-like follicular/fibroblastic dendritic cell sarcoma (IPT-like FDCS) is a rare EBV-associated variant of follicular dendritic cell sarcoma, usually arising in the liver or spleen and characterized by a favourable prognosis. The neoplastic cells show variable follicu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | Infectious Agents and Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13027-022-00474-8 |
| _version_ | 1797977620742144000 |
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| author | Francesca Pagliuca Andrea Ronchi Annamaria Auricchio Eva Lieto Renato Franco |
| author_facet | Francesca Pagliuca Andrea Ronchi Annamaria Auricchio Eva Lieto Renato Franco |
| author_sort | Francesca Pagliuca |
| collection | DOAJ |
| description | Abstract Inflammatory pseudotumour-like follicular/fibroblastic dendritic cell sarcoma (IPT-like FDCS) is a rare EBV-associated variant of follicular dendritic cell sarcoma, usually arising in the liver or spleen and characterized by a favourable prognosis. The neoplastic cells show variable follicular dendritic cell or fibroblastic reticular cell differentiation and their immunoprofile is still poorly characterized. We describe a case of splenic IPT-like FDCS with unexpected CD31 expression and provide a concise review of English literature on the topic. |
| first_indexed | 2024-04-11T05:10:19Z |
| format | Article |
| id | doaj.art-f987047cfbde43e1ae0a4a05500badbd |
| institution | Directory Open Access Journal |
| issn | 1750-9378 |
| language | English |
| last_indexed | 2024-04-11T05:10:19Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Infectious Agents and Cancer |
| spelling | doaj.art-f987047cfbde43e1ae0a4a05500badbd2022-12-25T12:05:53ZengBMCInfectious Agents and Cancer1750-93782022-12-011711510.1186/s13027-022-00474-8Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virusFrancesca Pagliuca0Andrea Ronchi1Annamaria Auricchio2Eva Lieto3Renato Franco4Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”Division of Gastrointestinal Tract Surgical Oncology, Department of Translational Medical Sciences, University of Campania ‘Luigi Vanvitelli’Division of Gastrointestinal Tract Surgical Oncology, Department of Translational Medical Sciences, University of Campania ‘Luigi Vanvitelli’Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”Abstract Inflammatory pseudotumour-like follicular/fibroblastic dendritic cell sarcoma (IPT-like FDCS) is a rare EBV-associated variant of follicular dendritic cell sarcoma, usually arising in the liver or spleen and characterized by a favourable prognosis. The neoplastic cells show variable follicular dendritic cell or fibroblastic reticular cell differentiation and their immunoprofile is still poorly characterized. We describe a case of splenic IPT-like FDCS with unexpected CD31 expression and provide a concise review of English literature on the topic.https://doi.org/10.1186/s13027-022-00474-8Inflammatory pseudotumour-like follicular/fibroblastic dendritic cell sarcomaEpstein-Barr virusImmunohistochemistry |
| spellingShingle | Francesca Pagliuca Andrea Ronchi Annamaria Auricchio Eva Lieto Renato Franco Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virus Infectious Agents and Cancer Inflammatory pseudotumour-like follicular/fibroblastic dendritic cell sarcoma Epstein-Barr virus Immunohistochemistry |
| title | Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virus |
| title_full | Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virus |
| title_fullStr | Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virus |
| title_full_unstemmed | Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virus |
| title_short | Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virus |
| title_sort | inflammatory pseudotumor like follicular fibroblastic dendritic cell sarcoma focus on immunohistochemical profile and association with epstein barr virus |
| topic | Inflammatory pseudotumour-like follicular/fibroblastic dendritic cell sarcoma Epstein-Barr virus Immunohistochemistry |
| url | https://doi.org/10.1186/s13027-022-00474-8 |
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