Peptide P5 (residues 628–683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection

Peptide P5 (residues 628–683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection

<p>Abstract</p> <p>The membrane proximal region (MPR) of the transmembrane subunit, gp41, of the HIV envelope glycoprotein plays a critical role in HIV-1 infection of CD4<sup>+</sup> target cells and CD4-independent mucosal entry. It contains continuous epitopes recogni...

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Bibliographic Details
Main Authors: Clavel François, Labrosse Beatrice, Alfsen Annette, Tudor Daniela, Yu Huifeng, Bomsel Morgane
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/93

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