Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies

Introduction: The aim of this systematic review is to analyse the effect of physico-chemical properties of calcium silicate-based sealers in comparison to epoxy resin sealers in permanent teeth using a single-cone obturation technique. Methods: The study was conducted according to the guidelines of...

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Main Authors: Viresh Chopra, Graham Davis, Aylin Baysan
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/15/1/229
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author Viresh Chopra
Graham Davis
Aylin Baysan
author_facet Viresh Chopra
Graham Davis
Aylin Baysan
author_sort Viresh Chopra
collection DOAJ
description Introduction: The aim of this systematic review is to analyse the effect of physico-chemical properties of calcium silicate-based sealers in comparison to epoxy resin sealers in permanent teeth using a single-cone obturation technique. Methods: The study was conducted according to the guidelines of Cochrane Handbook for Systematic Reviews of Interventions and Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement. Literature search was performed using the PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, DOAJ, Open Gray with no language restrictions until October 2020. Two reviewers assessed the studies for eligibility. Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) was carried out to assess the evidence. Meta-analysis of the pooled data with subgroups was performed using the RevMan software (<i>p</i> < 0.05). Results: Results from the 28 included studies showed that the mean difference in adaptation to root canal walls (marginal adaptation, interfacial gaps and void volume) for both sealers were non-significant. However, void volume values showed a significant mean difference (<i>p</i> < 0.00001) favouring the calcium silicate-based sealers. The pooled meta-analysis reported statistically significant differences for apical microleakage (<i>p</i> = 0.0007) whilst there were non-significant mean differences for fracture resistance (<i>p</i> = 0.09) and push-out bond strength (<i>p</i> = 0.63). The heterogeneity among the included studies was 97% (I<sup>2</sup>). Conclusions: Within the limitations of this review, calcium silicate-based sealers demonstrated a similar or superior performance in comparison to resin-based sealers in terms of the physico-chemical properties.
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spelling doaj.art-f98e41d2ddb74168956d1aa3ed2fcaf22023-11-23T11:50:08ZengMDPI AGMaterials1996-19442021-12-0115122910.3390/ma15010229Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based StudiesViresh Chopra0Graham Davis1Aylin Baysan2Department of Adult Restorative Dentistry, Oman Dental College, Department of Oral Bioengineering, Queen Mary University, Mile End Rd. Bethnal Green, London E1 4NS, UKInstitute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, Mile End Rd. Bethnal Green, London E1 4NS, UKInstitute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, Mile End Rd. Bethnal Green, London E1 4NS, UKIntroduction: The aim of this systematic review is to analyse the effect of physico-chemical properties of calcium silicate-based sealers in comparison to epoxy resin sealers in permanent teeth using a single-cone obturation technique. Methods: The study was conducted according to the guidelines of Cochrane Handbook for Systematic Reviews of Interventions and Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement. Literature search was performed using the PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, DOAJ, Open Gray with no language restrictions until October 2020. Two reviewers assessed the studies for eligibility. Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) was carried out to assess the evidence. Meta-analysis of the pooled data with subgroups was performed using the RevMan software (<i>p</i> < 0.05). Results: Results from the 28 included studies showed that the mean difference in adaptation to root canal walls (marginal adaptation, interfacial gaps and void volume) for both sealers were non-significant. However, void volume values showed a significant mean difference (<i>p</i> < 0.00001) favouring the calcium silicate-based sealers. The pooled meta-analysis reported statistically significant differences for apical microleakage (<i>p</i> = 0.0007) whilst there were non-significant mean differences for fracture resistance (<i>p</i> = 0.09) and push-out bond strength (<i>p</i> = 0.63). The heterogeneity among the included studies was 97% (I<sup>2</sup>). Conclusions: Within the limitations of this review, calcium silicate-based sealers demonstrated a similar or superior performance in comparison to resin-based sealers in terms of the physico-chemical properties.https://www.mdpi.com/1996-1944/15/1/229calcium silicate-based sealersresin-based sealersphysico-chemicalmeta-analysisroot canal treatment
spellingShingle Viresh Chopra
Graham Davis
Aylin Baysan
Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies
Materials
calcium silicate-based sealers
resin-based sealers
physico-chemical
meta-analysis
root canal treatment
title Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies
title_full Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies
title_fullStr Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies
title_full_unstemmed Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies
title_short Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies
title_sort physico chemical properties of calcium silicate vs resin based sealers a systematic review and meta analysis of laboratory based studies
topic calcium silicate-based sealers
resin-based sealers
physico-chemical
meta-analysis
root canal treatment
url https://www.mdpi.com/1996-1944/15/1/229
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