Human monoclonal anti-protective antigen antibody for the low-dose post-exposure prophylaxis and treatment of Anthrax

Human monoclonal anti-protective antigen antibody for the low-dose post-exposure prophylaxis and treatment of Anthrax

Abstract Background Disease caused by Bacillus anthracis is often accompanied by high mortality primarily due to toxin-mediated injury. In the early disease course, anthrax toxins are secreted; thus, antibiotic use is limited to the early stage. In this regard, antibodies against the toxin component...

Full description

Bibliographic Details
Main Authors: Qi Tang, Siping Xiong, Xudong Liang, Xingwang Kuai, Yiwen Wang, Changjun Wang, Zhenqing Feng, Jin Zhu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Infectious Diseases
Subjects:
Anthrax
Full human antibody
Protective antigen (PA)
Lethal toxin
Neutralising
Online Access:http://link.springer.com/article/10.1186/s12879-018-3542-6

Internet

http://link.springer.com/article/10.1186/s12879-018-3542-6

Similar Items