Inter-cellular adhesion disruption and the RAS/RAF and beta-catenin signalling in lung cancer progression
<p>Abstract</p> <p>Cadherin cell adhesion molecules play an essential role in creating tight intercellular association and their loss has been correlated with poor prognosis in human cancer. Mutational activation of protein kinases and loss of cell adhesion occur together in human...
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| Format: | Article |
| Language: | English |
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BMC
2008-05-01
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| Series: | Cancer Cell International |
| Online Access: | http://www.cancerci.com/content/8/1/7 |