The Flavonoid Quercetin Induces AP-1 Activation in FRTL-5 Thyroid Cells

The Flavonoid Quercetin Induces AP-1 Activation in FRTL-5 Thyroid Cells

Previous studies have shown that quercetin inhibits thyroid function both in vitro and in vivo. An attempt to evaluate the effect of quercetin at the promoter level of the thyroid-specific genes led to the observation that this compound induces the basal activity of the reporter vector. Therefore, t...

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Bibliographic Details
Main Author: Cesidio Giuliani
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Antioxidants
Subjects:
quercetin
thyroid
FRTL-5
AP-1
gene expressions
PGL3 vectors
pSV0-CAT vector
Online Access:https://www.mdpi.com/2076-3921/8/5/112

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