Use of an Image Restoration Process to Improve Spatial Resolution in Bioluminescence Imaging
To improve spatial resolution in in vivo bioluminescence imaging, a photon scattering correction, image restoration method was tested. The chosen algorithm was tested on in vivo bioluminescent images acquired on three representative tumor models: subcutaneous, pulmonary, and disseminated peritoneal....
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publications
2011-11-01
|
| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.2310/7290.2011.00012 |
| _version_ | 1797283900223913984 |
|---|---|
| author | Sabrina Pesnel Smaïl Akkoul Roger Ledée Rémy Leconge Arnaud Pillon Anna Kruczynski Rachid Harba Stéphanie Lerondel Alain Le Pape |
| author_facet | Sabrina Pesnel Smaïl Akkoul Roger Ledée Rémy Leconge Arnaud Pillon Anna Kruczynski Rachid Harba Stéphanie Lerondel Alain Le Pape |
| author_sort | Sabrina Pesnel |
| collection | DOAJ |
| description | To improve spatial resolution in in vivo bioluminescence imaging, a photon scattering correction, image restoration method was tested. The chosen algorithm was tested on in vivo bioluminescent images acquired on three representative tumor models: subcutaneous, pulmonary, and disseminated peritoneal. Tumor size was chosen as a quantitative criterion, such that the tumor reference measurements (determined photographically or by computed tomography) were compared to those derived from bioluminescent images, before and after restoration. This technique allowed a significant reduction to be achieved in the relative error between reference measurements and dimensions derived from bioluminescent images. In addition, improved delineation of the tumor foci was achieved. The restoration method allows spatial resolution in bioluminescence imaging to be improved, with interesting perspectives in terms of staging and quantitation in experimental oncology. |
| first_indexed | 2024-03-07T17:37:31Z |
| format | Article |
| id | doaj.art-f99433b0e39845e19ab6ea41df0748ba |
| institution | Directory Open Access Journal |
| issn | 1536-0121 |
| language | English |
| last_indexed | 2024-03-07T17:37:31Z |
| publishDate | 2011-11-01 |
| publisher | SAGE Publications |
| record_format | Article |
| series | Molecular Imaging |
| spelling | doaj.art-f99433b0e39845e19ab6ea41df0748ba2024-03-02T16:39:37ZengSAGE PublicationsMolecular Imaging1536-01212011-11-011010.2310/7290.2011.0001210.2310_7290.2011.00012Use of an Image Restoration Process to Improve Spatial Resolution in Bioluminescence ImagingSabrina PesnelSmaïl AkkoulRoger LedéeRémy LecongeArnaud PillonAnna KruczynskiRachid HarbaStéphanie LerondelAlain Le PapeTo improve spatial resolution in in vivo bioluminescence imaging, a photon scattering correction, image restoration method was tested. The chosen algorithm was tested on in vivo bioluminescent images acquired on three representative tumor models: subcutaneous, pulmonary, and disseminated peritoneal. Tumor size was chosen as a quantitative criterion, such that the tumor reference measurements (determined photographically or by computed tomography) were compared to those derived from bioluminescent images, before and after restoration. This technique allowed a significant reduction to be achieved in the relative error between reference measurements and dimensions derived from bioluminescent images. In addition, improved delineation of the tumor foci was achieved. The restoration method allows spatial resolution in bioluminescence imaging to be improved, with interesting perspectives in terms of staging and quantitation in experimental oncology.https://doi.org/10.2310/7290.2011.00012 |
| spellingShingle | Sabrina Pesnel Smaïl Akkoul Roger Ledée Rémy Leconge Arnaud Pillon Anna Kruczynski Rachid Harba Stéphanie Lerondel Alain Le Pape Use of an Image Restoration Process to Improve Spatial Resolution in Bioluminescence Imaging Molecular Imaging |
| title | Use of an Image Restoration Process to Improve Spatial Resolution in Bioluminescence Imaging |
| title_full | Use of an Image Restoration Process to Improve Spatial Resolution in Bioluminescence Imaging |
| title_fullStr | Use of an Image Restoration Process to Improve Spatial Resolution in Bioluminescence Imaging |
| title_full_unstemmed | Use of an Image Restoration Process to Improve Spatial Resolution in Bioluminescence Imaging |
| title_short | Use of an Image Restoration Process to Improve Spatial Resolution in Bioluminescence Imaging |
| title_sort | use of an image restoration process to improve spatial resolution in bioluminescence imaging |
| url | https://doi.org/10.2310/7290.2011.00012 |
| work_keys_str_mv | AT sabrinapesnel useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging AT smailakkoul useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging AT rogerledee useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging AT remyleconge useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging AT arnaudpillon useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging AT annakruczynski useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging AT rachidharba useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging AT stephanielerondel useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging AT alainlepape useofanimagerestorationprocesstoimprovespatialresolutioninbioluminescenceimaging |