EXPERIMENTAL STUDY OF THE USE OF OSTEO-CELLULAR GRAFTS IN WRIST ARTHRODESIS
Introduction. Wrist arthrodesis is a surgery performed in advanced osteoarthritis of the wrist joint of various etiology, posttraumatic consequences or diseases of carpal bones. It is a rescue surgery and is performed with the cost of losing of range of movement, but remove the pain syndrome and inc...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Academy of Sciences of Moldova
2023-11-01
|
| Series: | Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale |
| Subjects: | |
| Online Access: | https://bulmed.md/bulmed/article/view/3589 |
| _version_ | 1797336272255057920 |
|---|---|
| author | Vitalie IACUBITCHII |
| author_facet | Vitalie IACUBITCHII |
| author_sort | Vitalie IACUBITCHII |
| collection | DOAJ |
| description | Introduction. Wrist arthrodesis is a surgery performed in advanced osteoarthritis of the wrist joint of various etiology, posttraumatic consequences or diseases of carpal bones. It is a rescue surgery and is performed with the cost of losing of range of movement, but remove the pain syndrome and increase the strength of the hand. Aim of study. Evaluation of osteo-cellular grafts (OCG) using in wrist arthrodesis in experimental study on laboratory animals. Material and Methods. The study was based on experimental research on 21 New Zealand rabbits, splited in 3 study groups. As methods of implementation of the study included: preparation of allogeneic demineralized bone grafts, bone marrow sampling and isolation of autologous stem cells, obtaining OCG, and performing 3 different techniques of wrist arthrodesis. Results. Imagistic results showed us, that the group were performed arthrodesis using combined graft with stem cells, the ankylosis were achieved faster. Histological examinations indicated more active involvement in the process of osteogenesis in the use of combined stem cell transplantation. Conclusion. Our study showed that compared to the control group, the arthrodesis of the wrist using the allograft have good impact in the process of osteogenesis, but the best results were performed by using allograft combined with stem cells. |
| first_indexed | 2024-03-08T08:51:52Z |
| format | Article |
| id | doaj.art-f996ade9084646b9a5f5bf535283be9a |
| institution | Directory Open Access Journal |
| issn | 1857-0011 |
| language | English |
| last_indexed | 2024-03-08T08:51:52Z |
| publishDate | 2023-11-01 |
| publisher | Academy of Sciences of Moldova |
| record_format | Article |
| series | Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale |
| spelling | doaj.art-f996ade9084646b9a5f5bf535283be9a2024-02-01T09:03:41ZengAcademy of Sciences of MoldovaBuletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale1857-00112023-11-0176212312710.52692/1857-0011.2023.2-76.213589EXPERIMENTAL STUDY OF THE USE OF OSTEO-CELLULAR GRAFTS IN WRIST ARTHRODESISVitalie IACUBITCHII0Nicolae Testemitanu State University of Medicine and PharmacyIntroduction. Wrist arthrodesis is a surgery performed in advanced osteoarthritis of the wrist joint of various etiology, posttraumatic consequences or diseases of carpal bones. It is a rescue surgery and is performed with the cost of losing of range of movement, but remove the pain syndrome and increase the strength of the hand. Aim of study. Evaluation of osteo-cellular grafts (OCG) using in wrist arthrodesis in experimental study on laboratory animals. Material and Methods. The study was based on experimental research on 21 New Zealand rabbits, splited in 3 study groups. As methods of implementation of the study included: preparation of allogeneic demineralized bone grafts, bone marrow sampling and isolation of autologous stem cells, obtaining OCG, and performing 3 different techniques of wrist arthrodesis. Results. Imagistic results showed us, that the group were performed arthrodesis using combined graft with stem cells, the ankylosis were achieved faster. Histological examinations indicated more active involvement in the process of osteogenesis in the use of combined stem cell transplantation. Conclusion. Our study showed that compared to the control group, the arthrodesis of the wrist using the allograft have good impact in the process of osteogenesis, but the best results were performed by using allograft combined with stem cells.https://bulmed.md/bulmed/article/view/3589wrist arthrodesisautologous stem cellsosteo-cellular graft |
| spellingShingle | Vitalie IACUBITCHII EXPERIMENTAL STUDY OF THE USE OF OSTEO-CELLULAR GRAFTS IN WRIST ARTHRODESIS Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale wrist arthrodesis autologous stem cells osteo-cellular graft |
| title | EXPERIMENTAL STUDY OF THE USE OF OSTEO-CELLULAR GRAFTS IN WRIST ARTHRODESIS |
| title_full | EXPERIMENTAL STUDY OF THE USE OF OSTEO-CELLULAR GRAFTS IN WRIST ARTHRODESIS |
| title_fullStr | EXPERIMENTAL STUDY OF THE USE OF OSTEO-CELLULAR GRAFTS IN WRIST ARTHRODESIS |
| title_full_unstemmed | EXPERIMENTAL STUDY OF THE USE OF OSTEO-CELLULAR GRAFTS IN WRIST ARTHRODESIS |
| title_short | EXPERIMENTAL STUDY OF THE USE OF OSTEO-CELLULAR GRAFTS IN WRIST ARTHRODESIS |
| title_sort | experimental study of the use of osteo cellular grafts in wrist arthrodesis |
| topic | wrist arthrodesis autologous stem cells osteo-cellular graft |
| url | https://bulmed.md/bulmed/article/view/3589 |
| work_keys_str_mv | AT vitalieiacubitchii experimentalstudyoftheuseofosteocellulargraftsinwristarthrodesis |