Detecting Early Cognitive Decline in Alzheimer’s Disease with Brain Synaptic Structural and Functional Evaluation

Detecting Early Cognitive Decline in Alzheimer’s Disease with Brain Synaptic Structural and Functional Evaluation

Early cognitive decline in patients with Alzheimer’s (AD) is associated with quantifiable structural and functional connectivity changes in the brain. AD dysregulation of Aβ and tau metabolism progressively disrupt normal synaptic function, leading to loss of synapses, decreased hippocampal synaptic...

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Bibliographic Details
Main Author:	Samo Ribarič
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	Biomedicines
Subjects:	Alzheimer’s disease ATN biomarkers cognitive decline functional connectivity hippocampus large-scale networks
Online Access:	https://www.mdpi.com/2227-9059/11/2/355

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