FAT3 Mutation Is Associated With Tumor Mutation Burden and Poor Prognosis in Esophageal Cancer

FAT3 Mutation Is Associated With Tumor Mutation Burden and Poor Prognosis in Esophageal Cancer

ObjectiveTo explore the mutated genes in esophageal cancer (ESCA), and evaluate its relationship with tumor mutation burden (TMB) and prognosis of ESCA, and analyze the advantages of FAT3 as a potential prognostic marker in ESCA.MethodsThe somatic mutation landscape was analyzed according to ESCA sa...

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Bibliographic Details
Main Authors: Zixin Guo, Xin Yan, Congkuan Song, Qingwen Wang, Yujin Wang, Xiao-Ping Liu, Jingyu Huang, Sheng Li, Weidong Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
FAT3
esophageal cancer
tumor mutation burden
prognostic marker
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.603660/full

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