USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration

USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration

Abstract Background Breast cancer (BC) is the most frequent tumor entity in women worldwide with a high chance of therapeutic response in early- and non-metastatic disease stages. Among all BC subtypes, triple-negative BC (TNBC) is the most challenging cancer subtype lacking effective molecular targ...

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Bibliographic Details
Main Authors: Evangelos Prokakis, Husam Bamahmoud, Shaishavi Jansari, Lena Fritsche, Alexander Dietz, Angela Boshnakovska, Peter Rehling, Steven A. Johnsen, Julia Gallwas, Florian Wegwitz
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
Breast cancer
TNBC
Epigenetics
USP22
OXPHOS
CSCs
Online Access:https://doi.org/10.1186/s12964-023-01441-5

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