Assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis: a case‒control study
Introduction: The Centers for Disease Control and Prevention has included asthma as a risk factor for developing severe coronavirus disease 2019 (COVID-19) illness. Respiratory viruses are known to run a more severe course in patients with underlying respiratory illnesses. However, the reports on th...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022-01-01
|
| Series: | Indian Journal of Paediatric Dermatology |
| Subjects: | |
| Online Access: | http://www.ijpd.in/article.asp?issn=2319-7250;year=2022;volume=23;issue=2;spage=123;epage=125;aulast=Mohta |
| _version_ | 1819022630831783936 |
|---|---|
| author | Alpana Mohta Bhikam Chand Ghiya Rajesh Dutt Mehta Vijeta Prasad |
| author_facet | Alpana Mohta Bhikam Chand Ghiya Rajesh Dutt Mehta Vijeta Prasad |
| author_sort | Alpana Mohta |
| collection | DOAJ |
| description | Introduction: The Centers for Disease Control and Prevention has included asthma as a risk factor for developing severe coronavirus disease 2019 (COVID-19) illness. Respiratory viruses are known to run a more severe course in patients with underlying respiratory illnesses. However, the reports on the association of atopic dermatitis and COVID-19 infection are contrasting. Aims and Objectives: We aimed at assessing the difference between the severity of COVID-19 illness in patients having concurrent atopic dermatitis compared to those without concurrent atopic dermatitis. Materials and Methods: Study subjects included real-time polymerase chain reaction (RT-PCR) positive COVID-19 patients under the age of 18 years. The patients were divided into two groups, namely, cases and controls. Cases included children with atopic dermatitis diagnosed according to revised Hanifin and Rajka criteria with positive COVID-19 RT-PCR report. Controls were age-and sex-matched children from the same center with COVID-19, without atopic dermatitis. Disease severity was compared between the two groups. In addition, the COVID-19 severity was correlated with the SCORAD in the "cases" group. Results: While assessing the severity of COVID-19 illness on the basis of computed tomography score and clinical severity, there was a higher proportion of "severe" illness in "cases" compared to "controls," however, the difference was statistically insignificant. There was no significant correlation between high SCORAD scores and severe COVID-19 illness. Conclusion: Our study contributes to the ever-growing data suggesting that atopic diathesis is not a risk factor for acquiring COVID-19. |
| first_indexed | 2024-12-21T04:26:03Z |
| format | Article |
| id | doaj.art-f99c208beec241179cd7405e7fb56af9 |
| institution | Directory Open Access Journal |
| issn | 2319-7250 |
| language | English |
| last_indexed | 2024-12-21T04:26:03Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Paediatric Dermatology |
| spelling | doaj.art-f99c208beec241179cd7405e7fb56af92022-12-21T19:16:04ZengWolters Kluwer Medknow PublicationsIndian Journal of Paediatric Dermatology2319-72502022-01-0123212312510.4103/ijpd.ijpd_147_21Assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis: a case‒control studyAlpana MohtaBhikam Chand GhiyaRajesh Dutt MehtaVijeta PrasadIntroduction: The Centers for Disease Control and Prevention has included asthma as a risk factor for developing severe coronavirus disease 2019 (COVID-19) illness. Respiratory viruses are known to run a more severe course in patients with underlying respiratory illnesses. However, the reports on the association of atopic dermatitis and COVID-19 infection are contrasting. Aims and Objectives: We aimed at assessing the difference between the severity of COVID-19 illness in patients having concurrent atopic dermatitis compared to those without concurrent atopic dermatitis. Materials and Methods: Study subjects included real-time polymerase chain reaction (RT-PCR) positive COVID-19 patients under the age of 18 years. The patients were divided into two groups, namely, cases and controls. Cases included children with atopic dermatitis diagnosed according to revised Hanifin and Rajka criteria with positive COVID-19 RT-PCR report. Controls were age-and sex-matched children from the same center with COVID-19, without atopic dermatitis. Disease severity was compared between the two groups. In addition, the COVID-19 severity was correlated with the SCORAD in the "cases" group. Results: While assessing the severity of COVID-19 illness on the basis of computed tomography score and clinical severity, there was a higher proportion of "severe" illness in "cases" compared to "controls," however, the difference was statistically insignificant. There was no significant correlation between high SCORAD scores and severe COVID-19 illness. Conclusion: Our study contributes to the ever-growing data suggesting that atopic diathesis is not a risk factor for acquiring COVID-19.http://www.ijpd.in/article.asp?issn=2319-7250;year=2022;volume=23;issue=2;spage=123;epage=125;aulast=Mohtaasthmaatopic dermatitiscoronavirus disease 2019pediatric coronavirus disease 2019severe acute respiratory syndrome-coronavirus-2 |
| spellingShingle | Alpana Mohta Bhikam Chand Ghiya Rajesh Dutt Mehta Vijeta Prasad Assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis: a case‒control study Indian Journal of Paediatric Dermatology asthma atopic dermatitis coronavirus disease 2019 pediatric coronavirus disease 2019 severe acute respiratory syndrome-coronavirus-2 |
| title | Assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis: a case‒control study |
| title_full | Assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis: a case‒control study |
| title_fullStr | Assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis: a case‒control study |
| title_full_unstemmed | Assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis: a case‒control study |
| title_short | Assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis: a case‒control study |
| title_sort | assessment of coronavirus disease 2019 severity in hospitalized pediatric patients with atopic dermatitis a case control study |
| topic | asthma atopic dermatitis coronavirus disease 2019 pediatric coronavirus disease 2019 severe acute respiratory syndrome-coronavirus-2 |
| url | http://www.ijpd.in/article.asp?issn=2319-7250;year=2022;volume=23;issue=2;spage=123;epage=125;aulast=Mohta |
| work_keys_str_mv | AT alpanamohta assessmentofcoronavirusdisease2019severityinhospitalizedpediatricpatientswithatopicdermatitisacasecontrolstudy AT bhikamchandghiya assessmentofcoronavirusdisease2019severityinhospitalizedpediatricpatientswithatopicdermatitisacasecontrolstudy AT rajeshduttmehta assessmentofcoronavirusdisease2019severityinhospitalizedpediatricpatientswithatopicdermatitisacasecontrolstudy AT vijetaprasad assessmentofcoronavirusdisease2019severityinhospitalizedpediatricpatientswithatopicdermatitisacasecontrolstudy |