Epigenetic Pathways in Human Disease: The Impact of DNA Methylation on Stress-Related Pathogenesis and Current Challenges in Biomarker Development

Epigenetic Pathways in Human Disease: The Impact of DNA Methylation on Stress-Related Pathogenesis and Current Challenges in Biomarker Development

HPA axis genes implicated in glucocorticoid regulation play an important role in regulating the physiological impact of social and environmental stress, and have become a focal point for investigating the role of glucocorticoid regulation in the etiology of disease. We conducted a systematic review...

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Bibliographic Details
Main Authors:	M. Austin Argentieri, Sairaman Nagarajan, Bobak Seddighzadeh, Andrea A. Baccarelli, Alexandra E. Shields
Format:	Article
Language:	English
Published:	Elsevier 2017-04-01
Series:	EBioMedicine
Subjects:	Methylation HPA axis Glucocorticoids NR3C1 HSD11β2 FKBP5 Adverse childhood experiences (ACE) Stress Hypertension Cancer PTSD Depression Alzheimer's
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396417301408

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