Pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiency

The term chronic pancreatitis (CP) is used to denote a group of chronic diseases of the pancreas of various etiology, predominantly inflammatory, with several phases of progress, and characterized by focal, segmental or diffuse degenerative and destructive changes in the exocrine component, atrophy...

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Main Authors: M. I. Shchyokina, M. S. Panchuk
Format: Article
Language:Russian
Published: Remedium Group LLC 2013-12-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/1130
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author M. I. Shchyokina
M. S. Panchuk
author_facet M. I. Shchyokina
M. S. Panchuk
author_sort M. I. Shchyokina
collection DOAJ
description The term chronic pancreatitis (CP) is used to denote a group of chronic diseases of the pancreas of various etiology, predominantly inflammatory, with several phases of progress, and characterized by focal, segmental or diffuse degenerative and destructive changes in the exocrine component, atrophy of glandular components (pancreocytes) and their replacement by connective (fibrous) tissue; changes in the pancreatic ductal system, formation of cysts and stones, with varying degree of exocrine and endocrine insufficiency. Over the past 30 years, the number of patients with CP doubled. While methods of diagnosis of chronic pancreatitis have improved, there is also an increase in alcohol consumption in some countries and a stronger impact of adverse environmental factors that weaken protective mechanisms of the body. Besides, CP has become much "younger". The average age of patients first diagnosed with CP decreased from 50 to 39 years; the percentage of women increased by 30%. The incidence of alcoholic pancreatitis rose from 40 to 75%.
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spelling doaj.art-f9a41a41f2cf46f8bd45d8337300845a2023-04-23T06:56:37ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902013-12-01010818810.21518/2079-701X-2013-10-81-881130Pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiencyM. I. Shchyokina0M. S. Panchuk1MEDSI group of companies, MoscowMEDSI group of companies, MoscowThe term chronic pancreatitis (CP) is used to denote a group of chronic diseases of the pancreas of various etiology, predominantly inflammatory, with several phases of progress, and characterized by focal, segmental or diffuse degenerative and destructive changes in the exocrine component, atrophy of glandular components (pancreocytes) and their replacement by connective (fibrous) tissue; changes in the pancreatic ductal system, formation of cysts and stones, with varying degree of exocrine and endocrine insufficiency. Over the past 30 years, the number of patients with CP doubled. While methods of diagnosis of chronic pancreatitis have improved, there is also an increase in alcohol consumption in some countries and a stronger impact of adverse environmental factors that weaken protective mechanisms of the body. Besides, CP has become much "younger". The average age of patients first diagnosed with CP decreased from 50 to 39 years; the percentage of women increased by 30%. The incidence of alcoholic pancreatitis rose from 40 to 75%.https://www.med-sovet.pro/jour/article/view/1130хронический панкреатитchronic pancreatitiscppancreocytes
spellingShingle M. I. Shchyokina
M. S. Panchuk
Pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiency
Медицинский совет
хронический панкреатит
chronic pancreatitis
cp
pancreocytes
title Pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiency
title_full Pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiency
title_fullStr Pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiency
title_full_unstemmed Pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiency
title_short Pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiency
title_sort pancreatic enzymes in the treatment of painful chronic pancreatitis with moderate exocrine insufficiency
topic хронический панкреатит
chronic pancreatitis
cp
pancreocytes
url https://www.med-sovet.pro/jour/article/view/1130
work_keys_str_mv AT mishchyokina pancreaticenzymesinthetreatmentofpainfulchronicpancreatitiswithmoderateexocrineinsufficiency
AT mspanchuk pancreaticenzymesinthetreatmentofpainfulchronicpancreatitiswithmoderateexocrineinsufficiency