Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic Variables
Objective: To investigate the relationship between oxytocin, menopause and obesity. Methods: A cross-sectional analysis on 56 obese (OB; 28 premenopausal) and 53 normal-weight women (NW; 27 premenopausal) was performed by measurement of oxytocin, leptin, adiponectin, gonadotropins, sex steroids, glu...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2018-10-01
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| Series: | Obesity Facts |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/492001 |
| _version_ | 1818300930676752384 |
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| author | Sabrina Maestrini Chiara Mele Stefania Mai Roberta Vietti Annamaria Di Blasio Luigi Castello Daniela Surico Gianluca Aimaretti Massimo Scacchi Paolo Marzullo |
| author_facet | Sabrina Maestrini Chiara Mele Stefania Mai Roberta Vietti Annamaria Di Blasio Luigi Castello Daniela Surico Gianluca Aimaretti Massimo Scacchi Paolo Marzullo |
| author_sort | Sabrina Maestrini |
| collection | DOAJ |
| description | Objective: To investigate the relationship between oxytocin, menopause and obesity. Methods: A cross-sectional analysis on 56 obese (OB; 28 premenopausal) and 53 normal-weight women (NW; 27 premenopausal) was performed by measurement of oxytocin, leptin, adiponectin, gonadotropins, sex steroids, glucose, and lipid homeostasis as well as DXA assessment of fat mass (%FM) and fat-free mass (FFM). Results: Women from NW and OB groups were comparable for age but differed in anthropometric measures. In our cohorts, menopause was not associated with changes in gluco-lipid homeostasis and %FM, while FFM was lower in postmenopausal women from both study groups (p Conclusions: Obesity and menopause are independent negative predictors of plasma oxytocin. Longitudinal studies should clarify the role of oxytocin on weight modifications experienced around and after menopause. |
| first_indexed | 2024-12-13T05:14:57Z |
| format | Article |
| id | doaj.art-f9a50dd5c8d64901b225430be593c042 |
| institution | Directory Open Access Journal |
| issn | 1662-4025 1662-4033 |
| language | English |
| last_indexed | 2024-12-13T05:14:57Z |
| publishDate | 2018-10-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Obesity Facts |
| spelling | doaj.art-f9a50dd5c8d64901b225430be593c0422022-12-21T23:58:27ZengKarger PublishersObesity Facts1662-40251662-40332018-10-0111542943910.1159/000492001492001Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic VariablesSabrina MaestriniChiara MeleStefania MaiRoberta ViettiAnnamaria Di BlasioLuigi CastelloDaniela SuricoGianluca AimarettiMassimo ScacchiPaolo MarzulloObjective: To investigate the relationship between oxytocin, menopause and obesity. Methods: A cross-sectional analysis on 56 obese (OB; 28 premenopausal) and 53 normal-weight women (NW; 27 premenopausal) was performed by measurement of oxytocin, leptin, adiponectin, gonadotropins, sex steroids, glucose, and lipid homeostasis as well as DXA assessment of fat mass (%FM) and fat-free mass (FFM). Results: Women from NW and OB groups were comparable for age but differed in anthropometric measures. In our cohorts, menopause was not associated with changes in gluco-lipid homeostasis and %FM, while FFM was lower in postmenopausal women from both study groups (p Conclusions: Obesity and menopause are independent negative predictors of plasma oxytocin. Longitudinal studies should clarify the role of oxytocin on weight modifications experienced around and after menopause.https://www.karger.com/Article/FullText/492001Body compositionObesityMenopauseOxytocin |
| spellingShingle | Sabrina Maestrini Chiara Mele Stefania Mai Roberta Vietti Annamaria Di Blasio Luigi Castello Daniela Surico Gianluca Aimaretti Massimo Scacchi Paolo Marzullo Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic Variables Obesity Facts Body composition Obesity Menopause Oxytocin |
| title | Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic Variables |
| title_full | Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic Variables |
| title_fullStr | Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic Variables |
| title_full_unstemmed | Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic Variables |
| title_short | Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic Variables |
| title_sort | plasma oxytocin concentration in pre and postmenopausal women its relationship with obesity body composition and metabolic variables |
| topic | Body composition Obesity Menopause Oxytocin |
| url | https://www.karger.com/Article/FullText/492001 |
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