Palmitic acid induces neurotoxicity and gliatoxicity in SH-SY5Y human neuroblastoma and T98G human glioblastoma cells

Palmitic acid induces neurotoxicity and gliatoxicity in SH-SY5Y human neuroblastoma and T98G human glioblastoma cells

Background Obesity-related central nervous system (CNS) pathologies like neuroinflammation and reactive gliosis are associated with high-fat diet (HFD) related elevation of saturated fatty acids like palmitic acid (PA) in neurons and astrocytes of the brain. Methods Human neuroblastoma cells SH-SY5Y...

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Bibliographic Details
Main Authors: Yee-Wen Ng, Yee-How Say
Format: Article
Language:English
Published: PeerJ Inc. 2018-04-01
Series:PeerJ
Subjects:
High-fat diet
Palmitic acid
Neuron
Astrocyte
Apoptosis
Oxidative stress
Online Access:https://peerj.com/articles/4696.pdf

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