No Plasmatic Proteomic Signature at Clinical Disease Onset Associated With 11 Year Clinical, Cognitive and MRI Outcomes in Relapsing-Remitting Multiple Sclerosis Patients

No Plasmatic Proteomic Signature at Clinical Disease Onset Associated With 11 Year Clinical, Cognitive and MRI Outcomes in Relapsing-Remitting Multiple Sclerosis Patients

Background: The clinical course of relapsing-remitting multiple sclerosis (RRMS) is highly heterogeneous and prognostic biomarkers at time of diagnosis are lacking.Objective: We investigated the predictive value of the plasma proteome at time of diagnosis in RRMS patients.Methods: The plasma proteom...

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Bibliographic Details
Main Authors: Claire Bridel, Anand J. C. Eijlers, Wessel N. van Wieringen, Marleen Koel-Simmelink, Cyra E. Leurs, Menno M. Schoonheim, Joep Killestein, Charlotte E. Teunissen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
multiple sclerosis
prognosis
proteomics
MRI
cognition
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00371/full

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