Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype.

Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype.

Multiple system atrophy (MSA) is a fatal, rapidly progressive neurodegenerative disease with (oligodendro-)glial cytoplasmic α-synuclein (α-syn) inclusions (GCIs). Peripheral neuropathies have been reported in up to 40% of MSA patients, the cause remaining unclear. In a transgenic MSA mouse model fe...

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Bibliographic Details
Main Authors: Daniela Kuzdas-Wood, Regina Irschick, Markus Theurl, Philipp Malsch, Norbert Mair, Christine Mantinger, Julia Wanschitz, Lars Klimaschewski, Werner Poewe, Nadia Stefanova, Gregor K Wenning
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4619736?pdf=render

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