Functional capacity of Shiga-toxin promoter sequences in eukaryotic cells.

Functional capacity of Shiga-toxin promoter sequences in eukaryotic cells.

Shiga toxins (Stx) are the main virulence factors in enterohemorrhagic Escherichia coli (EHEC) infections, causing diarrhea and hemolytic uremic syndrome (HUS). The genes encoding for Shiga toxin-2 (Stx2) are located in a bacteriophage. The toxin is formed by a single A subunit and five B subunits,...

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Main Authors: Leticia V Bentancor, Marcos F Bilen, María P Mejías, Romina J Fernández-Brando, Cecilia A Panek, Maria V Ramos, Gabriela C Fernández, Martín Isturiz, Pablo D Ghiringhelli, Marina S Palermo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3579788?pdf=render

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