Comparison of Efficacy between 120° and 180° Schlemm’s Canal Incision Microhook Ab Interno Trabeculotomy
We compared surgical outcomes in patients with either primary open-angle glaucoma or exfoliation glaucoma after undergoing combined phacoemulsification with either a 120° or 180° incision during a Schlemm’s canal microhook ab interno trabeculotomy (μLOT-Phaco). This retrospective comparative case se...
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| Format: | Article |
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MDPI AG
2021-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/14/3181 |
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| author | Naoki Okada Kazuyuki Hirooka Hiromitsu Onoe Yumiko Murakami Hideaki Okumichi Yoshiaki Kiuchi |
| author_facet | Naoki Okada Kazuyuki Hirooka Hiromitsu Onoe Yumiko Murakami Hideaki Okumichi Yoshiaki Kiuchi |
| author_sort | Naoki Okada |
| collection | DOAJ |
| description | We compared surgical outcomes in patients with either primary open-angle glaucoma or exfoliation glaucoma after undergoing combined phacoemulsification with either a 120° or 180° incision during a Schlemm’s canal microhook ab interno trabeculotomy (μLOT-Phaco). This retrospective comparative case series examined 52 μLOT-Phaco eyes that underwent surgery between September 2017 and December 2020. Surgical qualified success was defined as an intraocular pressure (IOP) of ≤20 mmHg, ≥20% IOP reduction with IOP-lowering medications, and no additional glaucoma surgery. Success rates were evaluated by Kaplan-Meier survival analysis. The number of postoperative IOP-lowering medications and occurrence of complications were also assessed. Mean preoperative IOP in the 120° group was 16.9 ± 7.6 mmHg, which significantly decreased to 10.9 ± 2.7 mmHg (<i>p</i> < 0.01) and 11.1 ± 3.1 mmHg (<i>p</i> = 0.01) at 12 and 24 months, respectively. The mean number of preoperative IOP-lowering medications significantly decreased from 2.8 ± 1.4 to 1.4 ± 1.4 (<i>p</i> < 0.01) at 24 months. Mean preoperative IOP in the 180° group was 17.1 ± 7.0 mmHg, which significantly decreased to 12.1 ± 3.2 mmHg (<i>p</i> = 0.02) and 12.9 ± 1.4 mmHg (<i>p</i> = 0.01) at 12 and 24 months, respectively. The mean number of preoperative IOP-lowering medications significantly decreased from 2.9 ± 1.2 to 1.4 ± 1.5 (<i>p</i> < 0.01) at 24 months. The probability of qualified success at 24 months in the 120° and 180° groups was 50.4% and 54.6%, respectively (<i>p</i> = 0.58). There was no difference observed for hyphema formation or IOP spikes. Surgical outcomes were not significantly different between the 120° and 180° incisions in Schlemm’s canal. |
| first_indexed | 2024-03-10T09:35:52Z |
| format | Article |
| id | doaj.art-f9b400896e744c4eae25e2fd9a228974 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T09:35:52Z |
| publishDate | 2021-07-01 |
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| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-f9b400896e744c4eae25e2fd9a2289742023-11-22T04:07:57ZengMDPI AGJournal of Clinical Medicine2077-03832021-07-011014318110.3390/jcm10143181Comparison of Efficacy between 120° and 180° Schlemm’s Canal Incision Microhook Ab Interno TrabeculotomyNaoki Okada0Kazuyuki Hirooka1Hiromitsu Onoe2Yumiko Murakami3Hideaki Okumichi4Yoshiaki Kiuchi5Department of Ophthalmology and Visual Science, Hiroshima University, Hiroshima 734-8551, JapanDepartment of Ophthalmology and Visual Science, Hiroshima University, Hiroshima 734-8551, JapanDepartment of Ophthalmology and Visual Science, Hiroshima University, Hiroshima 734-8551, JapanDepartment of Ophthalmology and Visual Science, Hiroshima University, Hiroshima 734-8551, JapanDepartment of Ophthalmology and Visual Science, Hiroshima University, Hiroshima 734-8551, JapanDepartment of Ophthalmology and Visual Science, Hiroshima University, Hiroshima 734-8551, JapanWe compared surgical outcomes in patients with either primary open-angle glaucoma or exfoliation glaucoma after undergoing combined phacoemulsification with either a 120° or 180° incision during a Schlemm’s canal microhook ab interno trabeculotomy (μLOT-Phaco). This retrospective comparative case series examined 52 μLOT-Phaco eyes that underwent surgery between September 2017 and December 2020. Surgical qualified success was defined as an intraocular pressure (IOP) of ≤20 mmHg, ≥20% IOP reduction with IOP-lowering medications, and no additional glaucoma surgery. Success rates were evaluated by Kaplan-Meier survival analysis. The number of postoperative IOP-lowering medications and occurrence of complications were also assessed. Mean preoperative IOP in the 120° group was 16.9 ± 7.6 mmHg, which significantly decreased to 10.9 ± 2.7 mmHg (<i>p</i> < 0.01) and 11.1 ± 3.1 mmHg (<i>p</i> = 0.01) at 12 and 24 months, respectively. The mean number of preoperative IOP-lowering medications significantly decreased from 2.8 ± 1.4 to 1.4 ± 1.4 (<i>p</i> < 0.01) at 24 months. Mean preoperative IOP in the 180° group was 17.1 ± 7.0 mmHg, which significantly decreased to 12.1 ± 3.2 mmHg (<i>p</i> = 0.02) and 12.9 ± 1.4 mmHg (<i>p</i> = 0.01) at 12 and 24 months, respectively. The mean number of preoperative IOP-lowering medications significantly decreased from 2.9 ± 1.2 to 1.4 ± 1.5 (<i>p</i> < 0.01) at 24 months. The probability of qualified success at 24 months in the 120° and 180° groups was 50.4% and 54.6%, respectively (<i>p</i> = 0.58). There was no difference observed for hyphema formation or IOP spikes. Surgical outcomes were not significantly different between the 120° and 180° incisions in Schlemm’s canal.https://www.mdpi.com/2077-0383/10/14/3181ab interno trabeculotomyintraocular pressureglaucomaincision in the Schlemm’s canal in degreespost-surgical complication |
| spellingShingle | Naoki Okada Kazuyuki Hirooka Hiromitsu Onoe Yumiko Murakami Hideaki Okumichi Yoshiaki Kiuchi Comparison of Efficacy between 120° and 180° Schlemm’s Canal Incision Microhook Ab Interno Trabeculotomy Journal of Clinical Medicine ab interno trabeculotomy intraocular pressure glaucoma incision in the Schlemm’s canal in degrees post-surgical complication |
| title | Comparison of Efficacy between 120° and 180° Schlemm’s Canal Incision Microhook Ab Interno Trabeculotomy |
| title_full | Comparison of Efficacy between 120° and 180° Schlemm’s Canal Incision Microhook Ab Interno Trabeculotomy |
| title_fullStr | Comparison of Efficacy between 120° and 180° Schlemm’s Canal Incision Microhook Ab Interno Trabeculotomy |
| title_full_unstemmed | Comparison of Efficacy between 120° and 180° Schlemm’s Canal Incision Microhook Ab Interno Trabeculotomy |
| title_short | Comparison of Efficacy between 120° and 180° Schlemm’s Canal Incision Microhook Ab Interno Trabeculotomy |
| title_sort | comparison of efficacy between 120° and 180° schlemm s canal incision microhook ab interno trabeculotomy |
| topic | ab interno trabeculotomy intraocular pressure glaucoma incision in the Schlemm’s canal in degrees post-surgical complication |
| url | https://www.mdpi.com/2077-0383/10/14/3181 |
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