T cell responses to control fungal infection in an immunological memory lens

In recent years, fungal vaccine research emanated significant findings in the field of antifungal T-cell immunity. The generation of effector T cells is essential to combat many mucosal and systemic fungal infections. The development of antifungal memory T cells is integral for controlling or preven...

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Main Authors: Jaishree Sharma, Srinivasu Mudalagiriyappa, Som Gowda Nanjappa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.905867/full
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author Jaishree Sharma
Srinivasu Mudalagiriyappa
Som Gowda Nanjappa
author_facet Jaishree Sharma
Srinivasu Mudalagiriyappa
Som Gowda Nanjappa
author_sort Jaishree Sharma
collection DOAJ
description In recent years, fungal vaccine research emanated significant findings in the field of antifungal T-cell immunity. The generation of effector T cells is essential to combat many mucosal and systemic fungal infections. The development of antifungal memory T cells is integral for controlling or preventing fungal infections, and understanding the factors, regulators, and modifiers that dictate the generation of such T cells is necessary. Despite the deficiency in the clear understanding of antifungal memory T-cell longevity and attributes, in this review, we will compile some of the existing literature on antifungal T-cell immunity in the context of memory T-cell development against fungal infections.
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spelling doaj.art-f9b748fcd88b460ba12a67451cd45da72022-12-22T04:25:46ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-09-011310.3389/fimmu.2022.905867905867T cell responses to control fungal infection in an immunological memory lensJaishree SharmaSrinivasu MudalagiriyappaSom Gowda NanjappaIn recent years, fungal vaccine research emanated significant findings in the field of antifungal T-cell immunity. The generation of effector T cells is essential to combat many mucosal and systemic fungal infections. The development of antifungal memory T cells is integral for controlling or preventing fungal infections, and understanding the factors, regulators, and modifiers that dictate the generation of such T cells is necessary. Despite the deficiency in the clear understanding of antifungal memory T-cell longevity and attributes, in this review, we will compile some of the existing literature on antifungal T-cell immunity in the context of memory T-cell development against fungal infections.https://www.frontiersin.org/articles/10.3389/fimmu.2022.905867/fullCD4+ T cellsCD8+ T cellsmemoryfungalvaccinationinfection
spellingShingle Jaishree Sharma
Srinivasu Mudalagiriyappa
Som Gowda Nanjappa
T cell responses to control fungal infection in an immunological memory lens
Frontiers in Immunology
CD4+ T cells
CD8+ T cells
memory
fungal
vaccination
infection
title T cell responses to control fungal infection in an immunological memory lens
title_full T cell responses to control fungal infection in an immunological memory lens
title_fullStr T cell responses to control fungal infection in an immunological memory lens
title_full_unstemmed T cell responses to control fungal infection in an immunological memory lens
title_short T cell responses to control fungal infection in an immunological memory lens
title_sort t cell responses to control fungal infection in an immunological memory lens
topic CD4+ T cells
CD8+ T cells
memory
fungal
vaccination
infection
url https://www.frontiersin.org/articles/10.3389/fimmu.2022.905867/full
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AT srinivasumudalagiriyappa tcellresponsestocontrolfungalinfectioninanimmunologicalmemorylens
AT somgowdananjappa tcellresponsestocontrolfungalinfectioninanimmunologicalmemorylens