Upregulation of leucine-rich alpha-2 glycoprotein: A key regulator of inflammation and joint fibrosis in patients with severe knee osteoarthritis

Upregulation of leucine-rich alpha-2 glycoprotein: A key regulator of inflammation and joint fibrosis in patients with severe knee osteoarthritis

IntroductionOsteoarthritis (OA) is a degenerative disease of the joints mainly affecting older individuals. Since the etiology behind the progression of OA is not well understood, several associated consequences, such as synovial joint stiffness and its progression due to joint fibrosis, are still p...

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Bibliographic Details
Main Authors: Ashish Sarkar, Debolina Chakraborty, Vijay Kumar, Rajesh Malhotra, Sagarika Biswas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
osteoarthritis
leucine-rich alpha-2 glycoprotein
fibrosis
biomarker
inflammation
SWATH
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1028994/full

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