Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity
The nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) multi-subunit complex is a highly abundant and central source of reactive oxygen species. NOX2 is a key enzyme of the innate immune system involved in antibacterial response, but excessive NOX2 activity is involved in oxidative stress...
| Hlavní autoři: | , , , |
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| Médium: | Článek |
| Jazyk: | English |
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Frontiers Media S.A.
2023-01-01
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| Edice: | Frontiers in Pharmacology |
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| On-line přístup: | https://www.frontiersin.org/articles/10.3389/fphar.2022.1075328/full |